HPV detection by in situ hybridisation in sinonasal inverted papilloma and squamous cell carcinoma.

IF 5.7 2区医学 Q1 OTORHINOLARYNGOLOGY

Rhinology Pub Date : 2026-10-10 DOI:10.4193/Rhin26.397

D Ginström, M Lundberg, J Hagström, C Haglund, E Auvinen, L M Aaltonen, S Viitasalo

引用次数: 0

Abstract

Dear Editor: Sinonasal inverted papilloma (SNIP) is a rare benign but locally aggressive tumour with an annual incidence of approximately 0.5-1.5/100 000, accounting for 4.7% of all sinonasal tumours. SNIP may recur and can transform into sinonasal squamous cell carcinoma (SNSCC) (1). Human papillomavirus (HPV) has been linked to SNIP recurrence and malignant progression, with a meta-analysis reporting the incidence of HPV in SNIP as 16.9% (2). This aligns with the results of our previous prospective study (17.8%), showing that the presence of HPV DNA was associated with SNIP recurrence in 90 patients undergoing surgery (3).

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鼻腔内翻性乳头状瘤和鳞状细胞癌的HPV原位杂交检测。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Rhinology 医学-耳鼻喉科学

CiteScore

15.80

自引率

9.70%

发文量

135

审稿时长

6-12 weeks

期刊介绍： Rhinology serves as the official Journal of the International Rhinologic Society and is recognized as one of the journals of the European Rhinologic Society. It offers a prominent platform for disseminating rhinologic research, reviews, position papers, task force reports, and guidelines to an international scientific audience. The journal also boasts the prestigious European Position Paper in Rhinosinusitis (EPOS), a highly influential publication first released in 2005 and subsequently updated in 2007, 2012, and most recently in 2020. Employing a double-blind peer review system, Rhinology welcomes original articles, review articles, and letters to the editor.