Long-term outcomes of preterm infants admitted to single-family rooms versus an open-bay neonatal intensive care unit: A randomized controlled trial.

IF 2.3 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Journal of Perinatology Pub Date : 2026-10-12 DOI:10.1038/s41372-026-02927-z

Michael J Vincer, Christy G Woolcott, Darlene J Inglis, Tanya M Myles, Susan M MacDonald, Jehier Afifi, C David Simpson, Satvinder Ghotra, Walid El-Naggar, Balpreet Singh, Danielle Styranko, Sharon Unger, Souvik Mitra, Douglas D McMillan, Jon S Dorling

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引用次数: 0

Abstract

Objective: To compare long-term outcomes of preterm infants in single-family room (SFR) vs. open-bay (OB) neonatal intensive care unit (NICU).

Study design: This randomized controlled trial took place in a tertiary NICU from April 2018 to June 2019. Infants <31 weeks gestation or ≤1500 grams birthweight were randomly assigned upon admission to SFR or OB. The primary outcome was death or neurodevelopmental impairment (NDI; cerebral palsy, language delay, cognitive delay, blindness, or deafness) at 36 months corrected age. Secondary outcomes were mortality, NDI components, and safety measures.

Results: Of 85 infants (43 SFR, 42 OB), there was no difference in primary outcome (40.5% SFR vs. 47.4% OB, p = 0.644). Secondary outcomes did not differ except mortality, which was lower in SFR (1/41, 2.4%) than OB (8/42, 19.0%), p = 0.029.

Conclusions: Composite outcome of death/NDI at 36 months corrected age was similar; however, reduction in mortality was noted in SFR. This trial was registered 6 Mar 2019 with ClinicalTrials.gov, NCT03867669 ( https://clinicaltrials.gov/search?cond=NCT03867669 ).

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早产儿入住单户病房与开放式新生儿重症监护病房的长期预后：一项随机对照试验。

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来源期刊

Journal of Perinatology 医学-妇产科学

CiteScore

5.40

自引率

6.90%

发文量

284

审稿时长

3-8 weeks

期刊介绍： The Journal of Perinatology provides members of the perinatal/neonatal healthcare team with original information pertinent to improving maternal/fetal and neonatal care. We publish peer-reviewed clinical research articles, state-of-the art reviews, comments, quality improvement reports, and letters to the editor. Articles published in the Journal of Perinatology embrace the full scope of the specialty, including clinical, professional, political, administrative and educational aspects. The Journal also explores legal and ethical issues, neonatal technology and product development. The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians and pediatric subspecialists, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists.