Adsorption Behavior of SARS-CoV-2 S1-RBD Protein on Na⁺/Ca²⁺-Saturated Montmorillonites.

IF 1.9 4区环境科学与生态学 Q3 ENVIRONMENTAL SCIENCES

Bulletin of Environmental Contamination and Toxicology Pub Date : 2026-10-10 DOI:10.1007/s00128-026-04340-w

Min Xu, Shiqi Li, Qian Chen, Xinhao Wang, Mingqiao Chen, Haoming Wang, Cheng Gu, Xinda Wu

{"title":"Adsorption Behavior of SARS-CoV-2 S1-RBD Protein on Na+/Ca2+-Saturated Montmorillonites.","authors":"Min Xu, Shiqi Li, Qian Chen, Xinhao Wang, Mingqiao Chen, Haoming Wang, Cheng Gu, Xinda Wu","doi":"10.1007/s00128-026-04340-w","DOIUrl":null,"url":null,"abstract":"SARS-CoV-2, known for its high transmissibility, spreads via aerosols, enabling long-term environmental persistence. Mineral particles, a key aerosol component, may interact with the virus, yet research remains limited. This study investigated the adsorption of SARS-CoV-2's receptor-binding domain (RBD) protein onto Na+- and Ca2+-montmorillonite (NaM, CaM) at pH 5 and 9 and ionic strengths of 1 mM and 10 mM. Results showed NaM adsorbed RBD faster and more efficiently than CaM. Higher ionic strength delayed adsorption equilibrium. Adsorption was lower at pH 5 than pH 9, suggesting contributions beyond electrostatic forces (e.g., hydrophobic interactions, hydrogen bonding). Theoretical calculations confirmed experiments and revealed Ca2+-mediated bridging between RBD and CaM. This work clarifies viral adsorption mechanisms on clay minerals, aiding environmental risk assessment of virus-mineral interactions.","PeriodicalId":501,"journal":{"name":"Bulletin of Environmental Contamination and Toxicology","volume":"117 4","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of Environmental Contamination and Toxicology","FirstCategoryId":"93","ListUrlMain":"https://doi.org/10.1007/s00128-026-04340-w","RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

SARS-CoV-2, known for its high transmissibility, spreads via aerosols, enabling long-term environmental persistence. Mineral particles, a key aerosol component, may interact with the virus, yet research remains limited. This study investigated the adsorption of SARS-CoV-2's receptor-binding domain (RBD) protein onto Na⁺- and Ca²⁺-montmorillonite (NaM, CaM) at pH 5 and 9 and ionic strengths of 1 mM and 10 mM. Results showed NaM adsorbed RBD faster and more efficiently than CaM. Higher ionic strength delayed adsorption equilibrium. Adsorption was lower at pH 5 than pH 9, suggesting contributions beyond electrostatic forces (e.g., hydrophobic interactions, hydrogen bonding). Theoretical calculations confirmed experiments and revealed Ca²⁺-mediated bridging between RBD and CaM. This work clarifies viral adsorption mechanisms on clay minerals, aiding environmental risk assessment of virus-mineral interactions.

查看原文本刊更多论文

SARS-CoV-2 S1-RBD蛋白在Na+/Ca2+饱和蒙脱石上的吸附行为

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Bulletin of Environmental Contamination and Toxicology 环境科学-毒理学

CiteScore

5.60

自引率

3.70%

发文量

230

审稿时长

1.7 months

期刊介绍： The Bulletin of Environmental Contamination and Toxicology(BECT) is a peer-reviewed journal that offers rapid review and publication. Accepted submissions will be presented as clear, concise reports of current research for a readership concerned with environmental contamination and toxicology. Scientific quality and clarity are paramount.