Effect of photon radiotherapy on microleakage and microhardness of nanohybrid resin composite restoration: an in vitro study.

IF 3.8 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

BMC Oral Health Pub Date : 2026-10-08 DOI:10.1186/s12903-026-09873-4

Manar Ahmed Khedr, Yasser Fathy Hussien, Mostafa A Hashem, Reem Gamal

{"title":"Effect of photon radiotherapy on microleakage and microhardness of nanohybrid resin composite restoration: an in vitro study.","authors":"Manar Ahmed Khedr, Yasser Fathy Hussien, Mostafa A Hashem, Reem Gamal","doi":"10.1186/s12903-026-09873-4","DOIUrl":null,"url":null,"abstract":"Background: Photon radiotherapy (RT) is widely used in the management of head and neck cancer (HNC) and may affect dental restorative materials. However, limited evidence is available regarding its effects on nanohybrid resin composite (RC) restorations. This research aimed to assess the impact of photon radiation treatment on microleakage (ML) and microhardness (MH) of nanohybrid RC restorations.Methods: A total of 54 samples were randomly divided into three groups (18 sample each): a control group (non-irradiated) and two RT groups exposed to 50 Gy (Gy) and 70 Gy of photon radiation. The radiation doses were delivered as a single dose, and post-irradiation assessments were performed immediately after irradiation. For ML, 30 extracted bovine incisors (n = 10 per group) were standardized, prepared with Class V cavities, and restored using a nanohybrid RC (Grandio, VOCO GmbH, Germany). Microleakage was assessed by dye penetration at the restoration interface using a stereomicroscope. For MH, 24 disc shaped composite samples (n = 8 per group) were evaluated using the Vickers MH test.Results: The median ML scores were 1.0, 1.0, and 2.0 for groups I, II, III, respectively (p = 0.029), while the median ML percentages were 17.93%, 24.75%, and 46.71%, respectively (p = 0.003). Before irradiation, mean MH values were 52.39 ± 2.41, 52.53 ± 1.51, and 52.23 ± 2.03, respectively (p = 0.959). Immediately after irradiation, these values increased to 53.60 ± 1.09, 62.90 ± 3.09, and 72.20 ± 5.53, respectively (p < 0.001).Conclusions: Under the conditions of this in vitro study, photon RT was associated with increased ML at 70 Gy of nanohybrid RC, whereas MH significantly increased following irradiation at both 50 and 70 Gy.","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"26 1","pages":""},"PeriodicalIF":3.8000,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13653397/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Oral Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12903-026-09873-4","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Photon radiotherapy (RT) is widely used in the management of head and neck cancer (HNC) and may affect dental restorative materials. However, limited evidence is available regarding its effects on nanohybrid resin composite (RC) restorations. This research aimed to assess the impact of photon radiation treatment on microleakage (ML) and microhardness (MH) of nanohybrid RC restorations.

Methods: A total of 54 samples were randomly divided into three groups (18 sample each): a control group (non-irradiated) and two RT groups exposed to 50 Gy (Gy) and 70 Gy of photon radiation. The radiation doses were delivered as a single dose, and post-irradiation assessments were performed immediately after irradiation. For ML, 30 extracted bovine incisors (n = 10 per group) were standardized, prepared with Class V cavities, and restored using a nanohybrid RC (Grandio, VOCO GmbH, Germany). Microleakage was assessed by dye penetration at the restoration interface using a stereomicroscope. For MH, 24 disc shaped composite samples (n = 8 per group) were evaluated using the Vickers MH test.

Results: The median ML scores were 1.0, 1.0, and 2.0 for groups I, II, III, respectively (p = 0.029), while the median ML percentages were 17.93%, 24.75%, and 46.71%, respectively (p = 0.003). Before irradiation, mean MH values were 52.39 ± 2.41, 52.53 ± 1.51, and 52.23 ± 2.03, respectively (p = 0.959). Immediately after irradiation, these values increased to 53.60 ± 1.09, 62.90 ± 3.09, and 72.20 ± 5.53, respectively (p < 0.001).

Conclusions: Under the conditions of this in vitro study, photon RT was associated with increased ML at 70 Gy of nanohybrid RC, whereas MH significantly increased following irradiation at both 50 and 70 Gy.

查看原文本刊更多论文

光子放射治疗对纳米复合树脂修复体微渗漏和显微硬度的影响。

背景：光子放射治疗广泛应用于头颈癌（HNC）的治疗，并可能影响牙齿的修复材料。然而，关于其对纳米复合树脂（RC）修复体的影响，证据有限。本研究旨在评估光子辐射处理对纳米复合RC修复体微渗漏（ML）和显微硬度（MH）的影响。方法：将54份样本随机分为3组（每组18份）：对照组（未辐照）和50 Gy （Gy）和70 Gy光子辐射下的RT组。辐射剂量以单次剂量提供，辐照后立即进行辐照后评估。对于ML， 30个提取的牛门牙（每组n = 10）被标准化，用V级腔制备，并使用纳米混合RC （Grandio, VOCO GmbH，德国）修复。在立体显微镜下，通过染料在修复界面的渗透来评估微泄漏。对于MH，采用维氏MH检验对24个圆盘状复合材料样品（每组n = 8）进行评估。结果：I、II、III组ML评分中位数分别为1.0、1.0、2.0 (p = 0.029)， ML百分比中位数分别为17.93%、24.75%、46.71% （p = 0.003）。辐照前平均MH值分别为52.39±2.41、52.53±1.51、52.23±2.03 （p = 0.959）。结论：在体外实验条件下，在70 Gy辐照下，光子RT与纳米杂交RC的ML升高相关，而在50和70 Gy辐照下，MH均显著升高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

BMC Oral Health DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.90

自引率

6.90%

发文量

481

审稿时长

6-12 weeks

期刊介绍： BMC Oral Health is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of disorders of the mouth, teeth and gums, as well as related molecular genetics, pathophysiology, and epidemiology.