Extensive Perianal Basal Cell Carcinoma Presenting With Severe Anorectal Dysfunction.

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY

ACG Case Reports Journal Pub Date : 2026-10-09 eCollection Date: 2026-10-01 DOI:10.14309/crj.0000000000002361

Sebastian Arambulo-Castillo, Maria Alejandra Gutierrez-Luque, Josh Elefteratos, Lingyu Bao, Grace Kajita, Hilary Hertan

引用次数: 0

Abstract

Perianal basal cell carcinoma is an exceedingly rare malignancy that may mimic benign anorectal conditions or anal squamous cell carcinoma. We report an 84-year-old man with a several-year history of a progressively enlarging circumferential perianal lesion, complicated by constipation, chronic fecal incontinence, bleeding, and significant weight loss. Examination revealed a 15 cm ulcerated tumor involving the entire anal verge, with biopsy confirming basal cell carcinoma and sparing of the anal canal mucosa. Imaging showed fecal impaction and perianal soft tissue thickening without metastasis. Given extensive involvement, vismodegib was initiated. This case highlights the importance of early biopsy of atypical perianal lesions.

查看原文本刊更多论文

广泛的肛周基底细胞癌表现为严重的肛肠功能障碍。

肛门周围基底细胞癌是一种非常罕见的恶性肿瘤，它可能类似于良性肛门直肠疾病或肛门鳞状细胞癌。我们报告一位84岁的男性患者，他的肛门周围病变逐渐扩大，并伴有便秘、慢性大小便失禁、出血和明显的体重减轻。检查发现一个15厘米溃疡肿瘤累及整个肛门边缘，活检证实基底细胞癌和保留肛管粘膜。影像显示大便嵌塞及肛周软组织增厚，无转移。鉴于广泛参与，开始使用vismodegib。本病例强调了非典型肛周病变早期活检的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.