Albendazole ointment: a potentially safe, painless, and effective therapy for cutaneous larva migrans during pregnancy.

IF 1.6 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Alfonso Gotor-Rivera, Elena Porres-López, Pablo L Ortiz-Romero, María Asunción Pérez-Jacoiste Asín
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引用次数: 0

Abstract

Objectives: We report two cases of cutaneous larva migrans in pregnant women.

Methods: Due to pregnancy, systemic therapy was not considered. Limited efficacy of cryotherapy and unavailability of topical thiabendazole led to the in-office preparation of 10% albendazole ointment.

Results: Application of this compound thrice daily under occlusion for 10 days led to complete resolution without recurrence. No safety signals were reported during pregnancy follow-up and until birth.

Conclusion: Topical albendazole may be an effective, safe, and painless treatment of cutaneous larva migrans. Larger studies are needed to confirm its efficacy and safety, though previous experience supports its use.

阿苯达唑软膏:一个潜在的安全,无痛,有效的治疗皮肤幼虫迁移在怀孕期间。
目的:我们报告两例孕妇皮肤幼虫迁移。方法:因妊娠,未考虑全身治疗。冷冻治疗的有限疗效和局部噻苯达唑的不可获得导致在办公室制备10%阿苯达唑软膏。结果:该药每日应用三次,连续10天,完全消除,无复发。在妊娠随访期间和分娩前未见安全信号。结论:阿苯达唑是一种有效、安全、无痛的治疗皮肤迁移幼虫的方法。虽然以前的经验支持使用,但需要更大规模的研究来证实其有效性和安全性。
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来源期刊
Transactions of The Royal Society of Tropical Medicine and Hygiene
Transactions of The Royal Society of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生
CiteScore
4.00
自引率
9.10%
发文量
115
审稿时长
4-8 weeks
期刊介绍: Transactions of the Royal Society of Tropical Medicine and Hygiene publishes authoritative and impactful original, peer-reviewed articles and reviews on all aspects of tropical medicine.
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