Association between smoking cessation duration and prediabetes among former smokers: A secondary dataset analysis of the Korea National Health and Nutrition Examination Survey 2015-2024.

IF 2.4 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Tobacco Induced Diseases Pub Date : 2026-10-07 eCollection Date: 2026-01-01 DOI:10.18332/tid/236889

Minchai Kim, Hongji Lee, Yeon Woo Oh, Eun-Cheol Park

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引用次数: 0

Abstract

Introduction: Prediabetes is an early stage of glucose dysregulation and an important target for diabetes prevention. Smoking is a modifiable risk factor for impaired glucose metabolism, and metabolic risk after smoking cessation may differ by time since cessation. This study examined the association between smoking cessation duration and prediabetes among Korean adult former smokers.

Methods: This secondary dataset analysis used data from the Korea National Health and Nutrition Examination Survey (KNHANES), a nationwide cross-sectional survey conducted in the Republic of Korea, from 2015 to 2024, and included 8790 former smokers aged ≥30 years without diabetes. Smoking cessation duration was the primary exposure, and prediabetes was defined as fasting plasma glucose 100-125 mg/dL or hemoglobin A1c 5.7-6.4%. Sex-stratified multivariable logistic regression models were used to estimate adjusted odds ratios (AORs) and 95% confidence intervals (CIs).

Results: Prediabetes was present in 4205 men (56.9%) and 478 women (34.3%). Among men, each additional year since smoking cessation was associated with lower odds of prediabetes (AOR=0.99; 95% CI: 0.99-1.00; p=0.019), whereas no significant association was observed among women (AOR=1.00; 95% CI: 0.99-1.02; p=0.554). In subgroup analyses among men, inverse associations were observed in those with 10-19 pack-years (AOR=0.99; 95% CI: 0.98-1.00) and ≥20 pack-years (AOR=0.99; 95% CI: 0.98-1.00).

Conclusions: Longer smoking cessation duration was associated with lower odds of prediabetes among Korean male former smokers, whereas no comparable association was observed among women. The association was more evident in men with greater cumulative smoking exposure. Because of the cross-sectional design, these findings should be interpreted as associations and do not establish a causal effect of smoking cessation duration on metabolic risk.

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来源期刊

Tobacco Induced Diseases SUBSTANCE ABUSE-PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

CiteScore

5.30

自引率

5.40%

发文量

审稿时长

12 weeks

期刊介绍： Tobacco Induced Diseases encompasses all aspects of research related to the prevention and control of tobacco use at a global level. Preventing diseases attributable to tobacco is only one aspect of the journal, whose overall scope is to provide a forum for the publication of research articles that can contribute to reducing the burden of tobacco induced diseases globally. To address this epidemic we believe that there must be an avenue for the publication of research/policy activities on tobacco control initiatives that may be very important at a regional and national level. This approach provides a very important "hands on" service to the tobacco control community at a global scale - as common problems have common solutions. Hence, we see ourselves as "connectors" within this global community. The journal hence encourages the submission of articles from all medical, biological and psychosocial disciplines, ranging from medical and dental clinicians, through health professionals to basic biomedical and clinical scientists.