Nosocomial outbreak of Ralstonia mannitolilytica associated with prefilled saline flush syringes distributed in Europe, Germany, March to September 2026.

IF 8.3 2区医学 Q1 INFECTIOUS DISEASES

Eurosurveillance Pub Date : 2026-10-01 DOI:10.2807/1560-7917.ES.2026.31.40.2600819

Sofia Burdi, Lukas Herrmann, Sophia N Koerdt, Silver A Wolf, Sandra Appelt, Mirco Sandfort, Barbara Maier, Sandra Reuter, Martin J Hug, Nicholas Jakob Böhm, Gizem Karadag, Georg Berndt, Achim Dörre, Vera Schwierzeck, Linda Behrends, Pascal Kreuzer, Julia Kuhn, Lukas Murajda, Saskia Roßbach, Susanne Kolbe-Busch, Cornelia Seidel, Patrick Jung, Grettel Chanto Chacón, Irina Zuschneid, Somayyeh Sedaghatjoo, Maximilian Driller Povill, Holger C Scholz, Alexander Mellmann, Tim Eckmanns, Josef Zündorf, Michael Hogardt, Sebastian Haller

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引用次数: 0

Abstract

A nosocomial outbreak of Ralstonia mannitolilytica bloodstream infections in Germany from March to September 2026 included 16 cases (≤ 6 allelic differences using core genome multilocus sequence typing) across seven hospitals. Epidemiological investigations supported by a large language model, identified prefilled saline flush syringes of one manufacturer as common exposure across all cases. The manufacturer initiated a temporary quarantine and suspension of use of this product. Because it was distributed to other countries, cases may have occurred elsewhere, prompting this report.

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2026年3月至9月在欧洲和德国分布的与预充盐水冲洗注射器相关的溶甘露醇拉尔斯顿菌的院内暴发

德国于2026年3月至9月爆发了一场医院内爆发的溶甘露醇拉尔斯顿菌血液感染，包括16例病例（使用核心基因组多位点序列分型，≤6个等位基因差异），涉及7家医院。在大型语言模型的支持下进行的流行病学调查确定，一家制造商的预充盐水冲洗注射器是所有病例的常见接触。制造商开始对该产品进行临时检疫和暂停使用。由于该病毒已传播到其他国家，因此其他地方可能也发生过病例，从而促成了本报告。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Eurosurveillance INFECTIOUS DISEASES-

CiteScore

32.70

自引率

2.10%

发文量

430

审稿时长

3-8 weeks

期刊介绍： Eurosurveillance is a European peer-reviewed journal focusing on the epidemiology, surveillance, prevention, and control of communicable diseases relevant to Europe.It is a weekly online journal, with 50 issues per year published on Thursdays. The journal includes short rapid communications, in-depth research articles, surveillance reports, reviews, and perspective papers. It excels in timely publication of authoritative papers on ongoing outbreaks or other public health events. Under special circumstances when current events need to be urgently communicated to readers for rapid public health action, e-alerts can be released outside of the regular publishing schedule. Additionally, topical compilations and special issues may be provided in PDF format.