Shorter Antibiotic Duration for Pseudomonas Bacteremia: A Call for Future Trials.

IF 8.3 1区医学 Q1 IMMUNOLOGY

Clinical Infectious Diseases Pub Date : 2026-10-09 DOI:10.1093/cid/ciag646

Arthur M Albuquerque, Carolina Santolia, Fernando G Zampieri, James M Brophy, Todd C Lee

引用次数: 0

Abstract

In bacteremia, 7-day treatment has been demonstrated as non-inferior to 14-days for mortality in most patients with uncomplicated Gram-negative bacteremia. This post-hoc Bayesian analysis found that the shorter antibiotic course may behave differently in patients with Pseudomonas aeruginosa bacteremia versus other gram-negatives. Future trials should generate more data in these infections.

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缩短假单胞菌菌血症的抗生素持续时间：对未来试验的呼吁。

在大多数无并发症的革兰氏阴性菌血症患者中，7天治疗的死亡率不低于14天。这种事后贝叶斯分析发现，较短的抗生素疗程可能在铜绿假单胞菌菌血症患者与其他革兰氏阴性患者中表现不同。未来的试验应该在这些感染中获得更多的数据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Infectious Diseases 医学-传染病学

CiteScore

25.00

自引率

2.50%

发文量

900

审稿时长

3 months

期刊介绍： Clinical Infectious Diseases (CID) is dedicated to publishing original research, reviews, guidelines, and perspectives with the potential to reshape clinical practice, providing clinicians with valuable insights for patient care. CID comprehensively addresses the clinical presentation, diagnosis, treatment, and prevention of a wide spectrum of infectious diseases. The journal places a high priority on the assessment of current and innovative treatments, microbiology, immunology, and policies, ensuring relevance to patient care in its commitment to advancing the field of infectious diseases.