Léo-Paul Tricou, Charles Hwang, Simon Talbot, Brian Hibler, Benjamin D. Leaker, Joshua Tam, Benjamin R. Freedman
{"title":"Antifibrotic biomaterials","authors":"Léo-Paul Tricou, Charles Hwang, Simon Talbot, Brian Hibler, Benjamin D. Leaker, Joshua Tam, Benjamin R. Freedman","doi":"10.1038/s44222-026-00489-5","DOIUrl":null,"url":null,"abstract":"Fibrosis is a major cause of organ dysfunction and mortality, yet current therapies rarely reverse established disease. Biomaterials offer new opportunities to locally modulate tissue-specific repair environments and guide healing away from scar formation and toward regeneration.","PeriodicalId":74248,"journal":{"name":"Nature reviews bioengineering","volume":"4 10","pages":"944-946"},"PeriodicalIF":42.7000,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature reviews bioengineering","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44222-026-00489-5","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Fibrosis is a major cause of organ dysfunction and mortality, yet current therapies rarely reverse established disease. Biomaterials offer new opportunities to locally modulate tissue-specific repair environments and guide healing away from scar formation and toward regeneration.