{"title":"Effects of environmental enrichment on outcomes of in vitro fertilization-embryo transfer in ICR mice.","authors":"Himeka Hayashi, Chiho Tsuchiya, Kotaro Unno, Hideaki Hayashi, Hiroshi Kitamura","doi":"10.1292/jvms.26-0263","DOIUrl":null,"url":null,"abstract":"<p><p>The effects of environmental enrichment (EE) on mother mice and their pups following in vitro fertilization-embryo transfer (IVF-ET) were evaluated. Mother mice were maintained with or without EE, which consisted of a house and three types of nest materials, immediately after embryo transfer into the fallopian tube. EE did not appear to have a beneficial effect on the surgical wounds of the mother mice. Although EE did not significantly affect litter sizes, it tends to increase the weaning rate. Additionally, EE increased 11% and 6% body weight gain in the male and female pups, respectively. EE tended to decrease fecal cortisol during the lactating period. Collectively, EE seems to improve the lactating environment of mother mice, thereby enhancing IVF-ET productivity.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Veterinary Medical Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1292/jvms.26-0263","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
The effects of environmental enrichment (EE) on mother mice and their pups following in vitro fertilization-embryo transfer (IVF-ET) were evaluated. Mother mice were maintained with or without EE, which consisted of a house and three types of nest materials, immediately after embryo transfer into the fallopian tube. EE did not appear to have a beneficial effect on the surgical wounds of the mother mice. Although EE did not significantly affect litter sizes, it tends to increase the weaning rate. Additionally, EE increased 11% and 6% body weight gain in the male and female pups, respectively. EE tended to decrease fecal cortisol during the lactating period. Collectively, EE seems to improve the lactating environment of mother mice, thereby enhancing IVF-ET productivity.
期刊介绍：
JVMS is a peer-reviewed journal and publishes a variety of papers on veterinary science from basic research to applied science and clinical research. JVMS is published monthly and consists of twelve issues per year. Papers are from the areas of anatomy, physiology, pharmacology, toxicology, pathology, immunology, microbiology, virology, parasitology, internal medicine, surgery, clinical pathology, theriogenology, avian disease, public health, ethology, and laboratory animal science. Although JVMS has played a role in publishing the scientific achievements of Japanese researchers and clinicians for many years, it now also accepts papers submitted from all over the world.
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