Generative estimation of conditional survival function.

IF 1.6 4区 数学 Q3 BIOLOGY
Biometrics Pub Date : 2026-10-07 DOI:10.1093/biomtc/ujag164
Xingyu Zhou, Wen Su, Changyu Liu, Yuling Jiao, Xingqiu Zhao, Jian Huang
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引用次数: 0

Abstract

We propose a deep generative approach to nonparametric estimation of conditional survival and hazard functions with censored data. The key idea of the proposed method is to first learn a conditional generator for the joint conditional distribution of the observed time and censoring indicator given covariates, and then construct the Kaplan-Meier and Nelson-Aalen estimators based on this conditional generator for conditional hazard and survival functions. Our method combines ideas from the recently developed deep generative learning and classical nonparametric estimation in survival analysis. We establish the convergence properties of the generative nonparametric estimators. Our numerical studies validate the proposed method.

条件生存函数的生成估计。
我们提出了一种基于截尾数据的条件生存函数和危险函数的非参数估计的深度生成方法。该方法的核心思想是首先学习一个条件生成器来求解观测时间和给定协变量的联合条件分布,然后基于该条件生成器构造条件危害函数和条件生存函数的Kaplan-Meier和Nelson-Aalen估计。我们的方法结合了最近发展的深度生成学习和生存分析中的经典非参数估计的思想。建立了生成非参数估计量的收敛性。我们的数值研究验证了所提出的方法。
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来源期刊
Biometrics
Biometrics 生物-生物学
CiteScore
2.70
自引率
5.30%
发文量
178
审稿时长
4-8 weeks
期刊介绍: The International Biometric Society is an international society promoting the development and application of statistical and mathematical theory and methods in the biosciences, including agriculture, biomedical science and public health, ecology, environmental sciences, forestry, and allied disciplines. The Society welcomes as members statisticians, mathematicians, biological scientists, and others devoted to interdisciplinary efforts in advancing the collection and interpretation of information in the biosciences. The Society sponsors the biennial International Biometric Conference, held in sites throughout the world; through its National Groups and Regions, it also Society sponsors regional and local meetings.
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