Erika Koh, Oluwadamilare Ajayi, Danielle McClanahan, Louise van der Weyden, Jamie Billington, Josephine IIott, David J Adams, Timothy McCalmont, Kevin White
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Abstract
Abstract: Primary cutaneous adnexal carcinomas are exceedingly rare in pediatric patients. A 12-year-old girl presented to the dermatology clinic with a congenital subcutaneous nodule on the left buttock. The patient underwent wide local excision, and histopathologic findings demonstrated large nodular aggregates of atypical basaloid cells with a sieve-like pattern. Immunohistochemical stains were positive for p63, AE1/AE3, β-catenin, and EMA. CK7, CK20, CD117, SOX-10, and Ber-Ep4 were negative. To the best of our knowledge upon review of the literature, we describe a new entity of an adnexal carcinoma with a cribriform pattern in a pediatric patient. Although there was no clinical evidence of recurrence at follow-up, the biologic potential of this tumor is unknown.
期刊介绍：
The American Journal of Dermatopathology offers outstanding coverage of the latest diagnostic approaches and laboratory techniques, as well as insights into contemporary social, legal, and ethical concerns. Each issue features review articles on clinical, technical, and basic science advances and illuminating, detailed case reports.
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