Concurrent presentation of distinct extranodal and splenic marginal zone lymphomas.

IF 1 4区医学 Q4 HEMATOLOGY

Journal of Hematopathology Pub Date : 2026-10-02 DOI:10.1007/s12308-026-00740-3

Jeremy D Grevet, Yong Zhang, Sam Sadigh, Austin I Kim

引用次数: 0

Abstract

Marginal zone lymphomas (MZLs) encompass extranodal, splenic, and nodal subtypes that are thought to clonally arise from antigen-exposed B-cells. Here, we present the case of a patient with a concurrent diagnosis of extranodal marginal zone lymphoma (EMZL) of the ocular adnexa and splenic marginal zone lymphoma (SMZL). These were identified on a core biopsy of the ocular adnexa and a bone marrow biopsy, respectively. While sequential occurrences of MZLs have been previously documented, this represents a concurrent diagnosis of two distinct MZLs.

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同时表现出明显的结外和脾边缘区淋巴瘤。

边缘区淋巴瘤（MZLs）包括结外、脾和淋巴结亚型，被认为是由抗原暴露的b细胞克隆产生的。在这里，我们提出了一个病例的患者同时诊断结外边缘区淋巴瘤（EMZL）的眼附件和脾边缘区淋巴瘤（SMZL）。这些分别是在眼附件的核心活检和骨髓活检中发现的。虽然先前有mzl的顺序发生记录，但这代表了两种不同mzl的并发诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Hematopathology HEMATOLOGYPATHOLOGY-PATHOLOGY

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： The Journal of Hematopathology aims at providing pathologists with a special interest in hematopathology with all the information needed to perform modern pathology in evaluating lymphoid tissues and bone marrow. To this end the journal publishes reviews, editorials, comments, original papers, guidelines and protocols, papers on ancillary techniques, and occasional case reports in the fields of the pathology, molecular biology, and clinical features of diseases of the hematopoietic system. The journal is the unique reference point for all pathologists with an interest in hematopathology. Molecular biologists involved in the expanding field of molecular diagnostics and research on lymphomas and leukemia benefit from the journal, too. Furthermore, the journal is of major interest for hematologists dealing with patients suffering from lymphomas, leukemias, and other diseases. The journal is unique in its true international character. Especially in the field of hematopathology it is clear that there are huge geographical variations in incidence of diseases. This is not only locally relevant, but due to globalization, relevant for all those involved in the management of patients.