Xueer Zhang, Pai Zheng, Yuesi Qin, E Liu, Yanjiao Xiong, Siyan Chen, Jing Guo
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引用次数: 0
Abstract
Curcumin (CUR) is a low-molecular-weight polyphenolic compound extracted from the rhizomes of the herb Curcuma longa. It exhibits a wide range of pharmacological activities, including anti-inflammatory, antioxidant, hypoglycemic, and antiviral effects. However, its poor solubility, low stability, and rapid metabolism significantly hinder its clinical application. In recent years, encapsulating drugs within natural polymer-based nanoparticle systems has significantly enhanced their penetration into deeper skin layers. Nanocarriers such as CUR-loaded nanoliposomes, polymeric nanoparticles, and polymeric micelles have notably improved its pharmacological activity and prolonged its retention time. This review summarizes the applications of CUR delivery systems in the treatment of inflammatory skin diseases and discusses the potential anti-inflammatory biological mechanisms underlying their therapeutic effects.
期刊介绍：
Phytotherapy Research is an internationally recognized pharmacological journal that serves as a trailblazing resource for biochemists, pharmacologists, and toxicologists. We strive to disseminate groundbreaking research on medicinal plants, pushing the boundaries of knowledge and understanding in this field.
Our primary focus areas encompass pharmacology, toxicology, and the clinical applications of herbs and natural products in medicine. We actively encourage submissions on the effects of commonly consumed food ingredients and standardized plant extracts. We welcome a range of contributions including original research papers, review articles, and letters.
By providing a platform for the latest developments and discoveries in phytotherapy, we aim to support the advancement of scientific knowledge and contribute to the improvement of modern medicine.
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