Glioma margins gain a third dimension before surgery ends.

IF 45.1 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Cell Pub Date : 2026-10-01 DOI:10.1016/j.cell.2026.09.002

Lingyan Shi

引用次数: 0

Abstract

In this issue of Cell, Liu et al. introduce ULTRA, which combines rapid tissue clearing, single-channel stimulated Raman scattering microscopy, and AI to generate cell-resolved three-dimensional virtual histology of intact glioma specimens in about 30 minutes-fast enough to expose depth-dependent infiltration before surgery ends.

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胶质瘤边缘在手术结束前获得第三个维度。

在这一期的Cell中，Liu等人介绍了ULTRA，该技术结合了快速组织清除、单通道刺激拉曼散射显微镜和人工智能，在大约30分钟内生成完整胶质瘤标本的细胞分辨三维虚拟组织学-足够快，可以在手术结束前暴露深度依赖浸润。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell 生物-生化与分子生物学

CiteScore

110.00

自引率

0.80%

发文量

396

审稿时长

2 months

期刊介绍： Cells is an international, peer-reviewed, open access journal that focuses on cell biology, molecular biology, and biophysics. It is affiliated with several societies, including the Spanish Society for Biochemistry and Molecular Biology (SEBBM), Nordic Autophagy Society (NAS), Spanish Society of Hematology and Hemotherapy (SEHH), and Society for Regenerative Medicine (Russian Federation) (RPO). The journal publishes research findings of significant importance in various areas of experimental biology, such as cell biology, molecular biology, neuroscience, immunology, virology, microbiology, cancer, human genetics, systems biology, signaling, and disease mechanisms and therapeutics. The primary criterion for considering papers is whether the results contribute to significant conceptual advances or raise thought-provoking questions and hypotheses related to interesting and important biological inquiries. In addition to primary research articles presented in four formats, Cells also features review and opinion articles in its "leading edge" section, discussing recent research advancements and topics of interest to its wide readership.