A S Yakimova, E N Rimskaya, A V Gorevoy, N P Makarova, E A Kalinina
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引用次数: 0
Abstract
A novel technology involving the donation of seminal plasma from fertile donors to improve the morphofunctional characteristics of human spermatozoa is proposed. The effects of seminal plasma from 7 donors, selected based on semen analysis parameters, were evaluated in spermatozoa from 31 men with infertility. Seminal plasma from three of the seven donors demonstrated a positive effect on recipient sperm motility. No effects, including adverse effects, were observed for the remaining donors. These findings suggest that donor selection should be based not only on standard semen analysis indicators but also on additional parameters, including seminal plasma composition. Further development and optimization of seminal plasma donation technology may prompt a revision of in vitro sperm preparation procedures and enhance the efficacy of assisted reproductive technology (ART) programs.
期刊介绍：
Bulletin of Experimental Biology and Medicine presents original peer reviewed research papers and brief reports on priority new research results in physiology, biochemistry, biophysics, pharmacology, immunology, microbiology, genetics, oncology, etc. Novel trends in science are covered in new sections of the journal - Biogerontology and Human Ecology - that first appeared in 2005.
World scientific interest in stem cells prompted inclusion into Bulletin of Experimental Biology and Medicine a quarterly scientific journal Cell Technologies in Biology and Medicine (a new Russian Academy of Medical Sciences publication since 2005). It publishes only original papers from the leading research institutions on molecular biology of stem and progenitor cells, stem cell as the basis of gene therapy, molecular language of cell-to-cell communication, cytokines, chemokines, growth and other factors, pilot projects on clinical use of stem and progenitor cells.
The Russian Volume Year is published in English from April.
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