Optical Biosensor-Based Detection of Drug-Resistant Bacteria Using Lateral Flow Immunoassay.

4区工程技术 Q2 Biochemistry, Genetics and Molecular Biology

Advances in biochemical engineering/biotechnology Pub Date : 2026-10-07 DOI:10.1007/10_2026_349

Sallahuddin Panhwar, Hareef Ahmed Keerio, Muhammad Usman Akram, Said Nawab, Ugur Tamer

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引用次数: 0

Abstract

The worldwide dissemination of antimicrobial-resistant pathogens via the food supply chain now represents a critical challenge for international health. Ensuring the integrity of food products necessitates the development of methodologies for the swift identification of resistant bacterial strains. Optical biosensing platforms utilizing lateral flow immunochromatographic assay (LFIA) principles have garnered substantial interest for their capacity to perform point-of-need detection via portable strips. This discussion evaluates contemporary advancements in optical LFIA technologies, specifically focusing on strategies for enhancing analytical sensitivity, selectivity, and the integration of antibody-modified substrates. Furthermore, this review categorizes specific drug-resistant bacterial targets and explores their detection through various practical and industrial lenses. The concluding segments emphasize the utility of LFIA as a versatile instrument for epidemiological tracking, detailed microbial assessment, and real-time surveillance within food production environments.

查看原文本刊更多论文

基于光学生物传感器的横向流动免疫法检测耐药细菌。

抗微生物药物耐药性病原体通过食品供应链在世界范围内传播，目前是对国际卫生的重大挑战。为了确保食品的完整性，需要开发快速鉴定耐药菌株的方法。利用横向流动免疫层析分析（LFIA）原理的光学生物传感平台因其通过便携式试纸条进行定点检测的能力而获得了极大的兴趣。本讨论评估了光学LFIA技术的当代进展，特别关注提高分析灵敏度、选择性和抗体修饰底物整合的策略。此外，本文还对耐药细菌的特异性靶点进行了分类，并探讨了通过各种实用和工业透镜检测耐药细菌的方法。结论部分强调了LFIA作为流行病学跟踪、详细微生物评估和食品生产环境实时监测的多功能工具的实用性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in biochemical engineering/biotechnology 工程技术-生物工程与应用微生物

CiteScore

5.70

自引率

0.00%

发文量

期刊介绍： Advances in Biochemical Engineering/Biotechnology reviews actual trends in modern biotechnology. Its aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required for chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. They give the state-of-the-art of a topic in a comprehensive way thus being a valuable source for the next 3 - 5 years. It also discusses new discoveries and applications.