{"title":"Programming flow anisotropy in hydrodynamic metamaterials <i>via</i> series-parallel equivalent fluidic networks.","authors":"Haixiang Pang, Yijia Ma, Yu-Hong Dong, Yiyun Cui, Kang-Kang Zhang","doi":"10.1039/d6lc00753h","DOIUrl":null,"url":null,"abstract":"<p><p>Precise microflow control underpins microfluidic technologies in precision medicine, yet conventional approaches rely on anisotropic materials or external fields, limiting fabrication simplicity and scalability. Unlike transformation-based or data-driven approaches, we demonstrate that flow anisotropy can be programmed through the layered organization of locally homogeneous, isotropic media <i>via</i> a series-parallel equivalent fluidic network (SPEFN) realized as single-medium metamaterials (SMMs). SPEFN provides an analytically invertible mapping from network topology to the macroscopic effective-viscosity tensor, from which a connectivity-controlled anisotropy law and an exact non-disturbance condition emerge as direct analytical consequences. We experimentally realize three monolithic SMM devices: a spiral-layered director, an annular cloak, and a fan-shaped concentrator. Particle-tracking velocimetry confirms the predicted responses across all devices, including ≈30° streamline reorientation and a concentrator velocity ratio of 1.37 <i>versus</i> a predicted value of 1.38. The cloak exhibits higher apparent suppression than predicted; tracer retention or adhesion visible in Movie S1 may partly explain this difference. The system further shows robust performance under strongly non-uniform inflow and sub-percent fabrication tolerances.</p>","PeriodicalId":85,"journal":{"name":"Lab on a Chip","volume":" ","pages":"5665-5689"},"PeriodicalIF":6.3000,"publicationDate":"2026-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lab on a Chip","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1039/d6lc00753h","RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
Precise microflow control underpins microfluidic technologies in precision medicine, yet conventional approaches rely on anisotropic materials or external fields, limiting fabrication simplicity and scalability. Unlike transformation-based or data-driven approaches, we demonstrate that flow anisotropy can be programmed through the layered organization of locally homogeneous, isotropic media via a series-parallel equivalent fluidic network (SPEFN) realized as single-medium metamaterials (SMMs). SPEFN provides an analytically invertible mapping from network topology to the macroscopic effective-viscosity tensor, from which a connectivity-controlled anisotropy law and an exact non-disturbance condition emerge as direct analytical consequences. We experimentally realize three monolithic SMM devices: a spiral-layered director, an annular cloak, and a fan-shaped concentrator. Particle-tracking velocimetry confirms the predicted responses across all devices, including ≈30° streamline reorientation and a concentrator velocity ratio of 1.37 versus a predicted value of 1.38. The cloak exhibits higher apparent suppression than predicted; tracer retention or adhesion visible in Movie S1 may partly explain this difference. The system further shows robust performance under strongly non-uniform inflow and sub-percent fabrication tolerances.
期刊介绍:
Lab on a Chip is the premiere journal that publishes cutting-edge research in the field of miniaturization. By their very nature, microfluidic/nanofluidic/miniaturized systems are at the intersection of disciplines, spanning fundamental research to high-end application, which is reflected by the broad readership of the journal. Lab on a Chip publishes two types of papers on original research: full-length research papers and communications. Papers should demonstrate innovations, which can come from technical advancements or applications addressing pressing needs in globally important areas. The journal also publishes Comments, Reviews, and Perspectives.