A chiral ferrocene-based P,Se-ligand for Cu-catalyzed 1,3-dipolar cycloaddition and Pd-catalyzed allylic substitution.

IF 2.8 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2026-10-21 DOI:10.1039/d6ob01039c

Ge-Yun You, Yan-Qin Wu, Hao-Song Wei, Hua-Jian Qin, Xing-Jing Huang, Chu-Yao Qiao, Hong-Kai Huang, Cui-Zhen Wang, Bin Feng

引用次数: 0

Abstract

A novel chiral ferrocenyl P,Se-ligand has been prepared through an efficient and simple operation. This ligand can be successfully applied in the Cu-catalyzed asymmetric 1,3-dipolar cycloaddition of imino esters with N-phenylmaleimide and Pd-catalyzed allylic substitution of C- and O-nucleophiles, producing a diverse range of products with high yields and enantioselectivities (up to 96% yield and 95% ee).

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铜催化1,3-偶极环加成和钯催化烯丙基取代的手性二茂铁P， se配体。

通过高效、简便的操作制备了一种新型手性二茂铁P - se配体。该配体可成功应用于cu催化的n -苯基马来酰亚胺亚胺不对称1,3-偶极环加成和pd催化的C-和o -亲核试剂的烯丙基取代，生产出多种高收率和对映选择性的产品（产率高达96%，ee高达95%）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.