GLP-1s among most effective in reducing weight in antipsychotic-treated patients

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Abstract

A systematic review and network meta-analysis encompassing 95 studies has found considerable variation among pharmacological interventions to reduce weight in antipsychotic-treated patients with schizophrenia. The glucagon-like peptide-1 (GLP-1) receptor agonists semaglutide, liraglutide, and exenatide were among the medications found to be associated with the greatest weight reduction with the highest-certainty evidence.

glp -1在抗精神病治疗患者中减肥最有效
一项包含95项研究的系统综述和网络荟萃分析发现,在抗精神病治疗的精神分裂症患者中,减轻体重的药物干预存在相当大的差异。胰高血糖素样肽-1 (GLP-1)受体激动剂西马鲁肽、利拉鲁肽和艾塞那肽是最有效的减重药物。
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