Negative impact of nasal septal perforation on quality of life: insights from 153 patients in a Spanish study

IF 1.2 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola Pub Date : 2026-09-01 Epub Date: 2026-10-01 DOI:10.1016/j.otorri.2026.512370

Berta Alegre Edo, María Jesús Rojas-Lechuga, Trinidad Arenas, Natalia Arango Cabezas, Octavio Garaycochea, Katherine Yuen-Ato, Isam Alobid

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引用次数: 0

Abstract

Objective

To evaluate the impact of nasal septal perforation (NSP) on sinonasal symptoms and quality of life (QoL) using patient-reported outcome measures.

Methods

A prospective observational study was conducted between 2018 and 2024 in two referral centres. Clinical, demographic, symptom-related, and QoL data were collected for all included patients.

Results

A total of 153 patients with NSP were included. The main aetiologies were intranasal cocaine abuse (n = 57; 37.3%), post-sinonasal surgery (n = 47; 30.7%), and rhinotillexomania (n = 31; 20.3%). The mean age was 47.8 years (SD 12.9; range 18.2–82.3), and 60.8% of patients were male. Anterior perforations were the most frequent location (n = 88; 57.5%). Mean perforation dimensions were 15.8 mm (SD 6.7) in height and 22.0 mm (SD 10.6) in length, with an estimated elliptic area of 312.9 mm² (SD 265.1; range 14.1–1272.3 mm²). The most frequent and severe symptoms reported on visual analogue scales were nasal obstruction (mean 58.3; SD 28.7), crusting (55.3; SD 34.9), and rhinorrhoea (44.8; SD 34.6). Quality of life was markedly impaired, with mean scores of 46.9 (SD 23.1) on the SNOT-22, 25.3 (SD 10.1) on the NOSE-Perf, and 24.1 (SD 10.1) on the SEPEQOL. The SF-36 physical and mental component summary scores were 45.0 (SD 10.5) and 40.5 (SD 14.2), respectively.

Conclusion

NSP is associated with a significant burden of sinonasal symptoms and a substantial impairment in quality of life. Patient-reported outcome measures demonstrate an impact on both physical and mental health domains, underscoring the importance of a comprehensive and multidisciplinary approach to the evaluation and management of patients with NSP.

查看原文本刊更多论文

鼻中隔穿孔对生活质量的负面影响：西班牙研究中153名患者的见解

目的评价鼻中隔穿孔（NSP）对鼻窦症状和生活质量（QoL）的影响。方法2018 - 2024年在两个转诊中心进行前瞻性观察研究。收集所有纳入患者的临床、人口学、症状相关和生活质量数据。结果共纳入NSP患者153例。主要病因为鼻内可卡因滥用（n = 57, 37.3%）、鼻后手术（n = 47, 30.7%）和鼻音躁狂（n = 31, 20.3%）。平均年龄47.8岁（SD 12.9，范围18.2 ~ 82.3），男性占60.8%。前路穿孔是最常见的部位（n = 88; 57.5%）。平均穿孔尺寸为高15.8 mm (SD 6.7)，长22.0 mm (SD 10.6)，估计椭圆面积为312.9 mm2 （SD 265.1；范围14.1-1272.3 mm2）。在视觉模拟量表上报告的最常见和最严重的症状是鼻塞（平均58.3;SD 28.7）、结痂（55.3;SD 34.9）和鼻漏（44.8;SD 34.6）。生活质量明显受损，SNOT-22的平均得分为46.9 (SD 23.1)， NOSE-Perf的平均得分为25.3 (SD 10.1)， SEPEQOL的平均得分为24.1 （SD 10.1）。SF-36生理和心理部分综合得分分别为45.0 （SD 10.5）和40.5 （SD 14.2）。结论nsp与鼻窦症状的严重负担和生活质量的严重损害有关。患者报告的结果测量显示了对身心健康领域的影响，强调了综合和多学科方法对NSP患者的评估和管理的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta otorrinolaringologica espanola OTORHINOLARYNGOLOGY-

CiteScore

1.40

自引率

20.00%

发文量

审稿时长

44 days

期刊介绍： Es la revista más importante en español dedicada a la especialidad. Ofrece progresos científicos y técnicos tanto a nivel de originales como de casos clínicos. Además, es la Publicación Oficial de la Sociedad Española de Otorrinolaringología y Patología Cérvico-Facial y está presente en los más prestigiosos índices de referencia.