A novel elicitor confers apple resistance to Glomerella cingulata through modulation of flavonoid metabolic pathways

IF 4.2 1区农林科学 Q1 AGRONOMY

Pest Management Science Pub Date : 2026-10-06 DOI:10.1002/ps.71356

Xinyue Cui,Mingjuan Yang,Yimeng Wang,Sen Lian,Weichao Ren,Pingliang Li,Na Liu,Baohua Li,Yaozhong Zhang,Caixia Wang

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引用次数: 0

Abstract

Abstract BACKGROUND Apple is a globally vital economic crop severely damaged by Glomerella leaf spot (GLS) caused by Glomerella cingulata . Current disease management relies heavily on chemical fungicides, but long‐term intensive application has triggered pathogen resistance, weakened control efficacy, aggravated pesticide residues and environmental contamination, and severely restricted the sustainable development of the apple industry. This study systematically investigated the disease resistance‐inducing potential of 3,6‐bis(1‐methylpropyl)‐2,5‐piperazinedione (BMP), a functional metabolite from plant endophytes. RESULTS BMP induced strong resistance against G. cingulata in detached apple leaves. Exogenous application of 0.1 μg mL −1 BMP reduced leaf lesion counts by 58.46% at the early GLS stage, persistently alleviated fruit disease severity and simultaneously promoted seedling root development and biomass accumulation. It functions by enhancing core defense enzyme activities and defense‐related gene expression, boosting flavonoid synthesis via down‐regulating MdMYB16 and establishing a multi‐layered defense system. CONCLUSION This work provides a novel strategy for apple disease management. It can reduce pesticide use, lower environmental impact, and improve fruit quality and safety, which fits the development concept of green agriculture and holds favorable application prospects. © 2026 Society of Chemical Industry.

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一种新的激发子通过调节类黄酮代谢途径赋予苹果对带状肾小球的抗性

摘要背景苹果是全球重要的经济作物，严重受到由带状肾小球（Glomerella cingulata）引起的GLS （Glomerella叶斑病）的危害。目前病害管理严重依赖化学杀菌剂，但长期大量使用导致病原菌产生抗性，防治效果减弱，农药残留和环境污染加剧，严重制约了苹果产业的可持续发展。本研究系统地研究了3,6 -二（1 -甲基丙基）- 2,5 -哌嗪二酮（BMP）的抗病诱导潜能，BMP是植物内生菌的一种功能性代谢物。结果BMP诱导离体苹果叶片对绿僵菌具有较强的抗性。外源施用0.1 μ mL−1 BMP可使GLS前期叶片损伤数减少58.46%，持续缓解果实病害严重程度，同时促进幼苗根系发育和生物量积累。其作用机制是通过下调MdMYB16，增强核心防御酶活性和防御相关基因表达，促进类黄酮合成，建立多层次防御体系。结论本研究为苹果病害管理提供了一种新的策略。可减少农药用量，降低环境影响，提高果实品质安全，符合绿色农业的发展理念，具有良好的应用前景。©2026化学工业协会。

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来源期刊

Pest Management Science 农林科学-昆虫学

CiteScore

7.90

自引率

9.80%

发文量

553

审稿时长

4.8 months

期刊介绍： Pest Management Science is the international journal of research and development in crop protection and pest control. Since its launch in 1970, the journal has become the premier forum for papers on the discovery, application, and impact on the environment of products and strategies designed for pest management. Published for SCI by John Wiley & Sons Ltd.