Left Ventricular Hypertrophy and Proteinuria in Hypertensive Patient with Retinopathy in Tertiary Care Hospital.

Abstract

Hypertensive retinopathy almost always associated with other target organ damage. Relationship of hypertensive retinopathy with left ventricular hypertrophy (LVH) and proteinuria was inconclusive in previous studies. The objective of the study was to assess the relation of Left Ventricular Hypertrophy and Proteinuria in Hypertensive Patient with Retinopathy in Tertiary Care Hospital. This is a cross-sectional observational study and conducted at the Department of Medicine and Cardiology in Dhaka Medical College Hospital. Study period was 01 year started from July 2016 to June 2017. Total 100 hypertensive retinopathy patients were included in the study. Following informed written consent, physical examination, relevant investigations were done. In all cases, Ethical issues were maintained properly and collected data were analyzed by SPSS 20.0. Among 100 participants, mean ±SD age was 57.15±12.989 years (age range 29-85) and 61.0% were male and 39.0% were female. Mean ±SD value of systolic and diastolic blood pressure in Grade (G)-1, G-2 and G-3 hypertension were 150.8±5.4) and 94.0±2.6 mm Hg, 170.3±4.9 and 101.0±4.7 mm Hg and 188.0±7.0 and 102.6±6.5 mm Hg respectively and it is significantly associated with severity of LVH (p value <0.001 in both systolic blood pressure (SBP) and diastolic blood pressure (DBP). Proteinuria is also associated with severity of hypertension (p<0.001) but there were no association of Hypertensive retinopathy with LVH and proteinuria (p value 0.32 and 0.27 respectively). Hypertensive retinopathy is not associated with LVH and proteinuria, though further large cohort is recommended for final comment.