Olfactory dysfunction in children is associated with atopic dermatitis and allergic rhinitis, but not bronchial asthma.

IF 5.1

Allergologie select Pub Date : 2026-09-10 eCollection Date: 2026-01-01 DOI:10.5414/ALX02644E

Elisabeth C Lohrer, Janine Gellrich, M Antonia Hinkelmann, Rene F Drosdek, Christian Vogelberg, Valentin A Schriever

{"title":"Olfactory dysfunction in children is associated with atopic dermatitis and allergic rhinitis, but not bronchial asthma.","authors":"Elisabeth C Lohrer, Janine Gellrich, M Antonia Hinkelmann, Rene F Drosdek, Christian Vogelberg, Valentin A Schriever","doi":"10.5414/ALX02644E","DOIUrl":null,"url":null,"abstract":"Aims: To investigate associations between olfactory dysfunction and atopic dermatitis (AD), allergic rhinitis (AR), and bronchial asthma (BA) in children.Materials and methods: In a prospective study, 250 children (6 - 17 years) with AD, AR, BA, combined atopy, or healthy controls (n = 50 each) were assessed using olfactory tests (\"Sniffin' Sticks\", \"U-Sniff\"), questionnaires, prick tests, and spirometry.Results: Atopic patients showed poorer odor identification than controls. Children with AD had impaired odor identification. AR patients displayed more hyposmia in threshold testing, but mean scores did not differ significantly. BA patients showed no significant impairment, though lung function correlated positively with olfactory performance.Conclusion: Pediatric AD and AR are associated with specific olfactory dysfunctions, whereas BA is not. Awareness of olfactory deficits in these groups is warranted; further studies should assess neurodevelopmental aspects in AD.","PeriodicalId":101298,"journal":{"name":"Allergologie select","volume":"10 ","pages":"226-233"},"PeriodicalIF":5.1000,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13621266/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Allergologie select","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5414/ALX02644E","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Aims: To investigate associations between olfactory dysfunction and atopic dermatitis (AD), allergic rhinitis (AR), and bronchial asthma (BA) in children.

Materials and methods: In a prospective study, 250 children (6 - 17 years) with AD, AR, BA, combined atopy, or healthy controls (n = 50 each) were assessed using olfactory tests ("Sniffin' Sticks", "U-Sniff"), questionnaires, prick tests, and spirometry.

Results: Atopic patients showed poorer odor identification than controls. Children with AD had impaired odor identification. AR patients displayed more hyposmia in threshold testing, but mean scores did not differ significantly. BA patients showed no significant impairment, though lung function correlated positively with olfactory performance.

Conclusion: Pediatric AD and AR are associated with specific olfactory dysfunctions, whereas BA is not. Awareness of olfactory deficits in these groups is warranted; further studies should assess neurodevelopmental aspects in AD.

查看原文本刊更多论文

儿童嗅觉功能障碍与特应性皮炎和变应性鼻炎有关，但与支气管哮喘无关。

目的：探讨儿童嗅觉功能障碍与特应性皮炎（AD）、变应性鼻炎（AR）和支气管哮喘（BA）的关系。材料和方法：在一项前瞻性研究中，使用嗅觉测试（“嗅探棒”、“U-Sniff”）、问卷调查、点刺试验和肺活量测定法对250名患有AD、AR、BA、合并特应性反应或健康对照（各50名）的儿童（6 - 17岁）进行评估。结果：特应性患者的气味识别能力较对照组差。AD患儿的气味识别能力受损。AR患者在阈值测试中表现出更多的低血症，但平均得分无显著差异。尽管肺功能与嗅觉表现呈正相关，但BA患者并未表现出明显的损害。结论：儿童AD和AR与特异性嗅觉功能障碍相关，而BA与特异性嗅觉功能障碍无关。意识到这些群体的嗅觉缺陷是必要的；进一步的研究应该评估阿尔茨海默病的神经发育方面。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Allergologie select

自引率

0.00%

发文量