A systematic review of the frequency of sleep evaluations, sleep disorders, and treatments among individuals with muscular dystrophy.

IF 3.4 3区医学 Q1 CLINICAL NEUROLOGY

Journal of Clinical Sleep Medicine Pub Date : 2026-09-29 DOI:10.1007/s44470-025-00041-z

Nedra Whitehead, Joyce T Alese, Christine Hill, Mike Enger, Jamie Zimmerman, Amy Moore, Julie Royer, Swamy Venkatash, Shiny Thomas, Barbara Do, James F Howard

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引用次数: 0

Abstract

Purpose: Review literature on the frequency of sleep disorders and receipt of sleep-related healthcare among individuals with muscular dystrophy.

Methods: Included: Population-Duchenne/Becker (DBMD), congenital (CMD), facioscapulohumeral (FSHD), limb-girdle (LGMD), or myotonic (DM) muscular dystrophy; Outcomes-frequency of sleep evaluations, disorders, or treatments; Language-English; Study type-original research, systematic review. Excluded: Sample <10, duplicate reports.

Information sources: PubMed and EBSCO, last searched March 7, 2023. Risk of bias assessment : Recruitment source or study inclusion selected for or against sleep symptoms or disorders.

Synthesis: Range and weighted average (low risk studies only) of outcome.

Results: We included 95 studies of sleep evaluations (7), disorders (94) or treatments (13) with a total of 7,964 participants. Studies reported on DM-61, DBMD-20, FSHD-9, CMD-1, LGMD-1, and multiple MD-3. One-half of people with DBMD (51%, 2 studies, 85 individuals) and over 60% of people with DM1 (65%, 2 studies, 327 individuals) had a sleep study. Measured by questionnaire, excessive daytime sleepiness frequency among adults with DM was 39% (DM2, 10, 284) to 65% (any DM, 6, 1195), 9% among controls (5, 199), and 6% to 13% among other MDs. Sleep apnea frequency was 11% (LGMD, 1, 18) to 65% (CMD, 1, 20). Assisted ventilation use was 5%-16% (DM).

Conclusions: Regular sleep evaluations may improve identification and treatment of sleep disorders and the physical and mental health of individuals with MD.

Other: Funding-US Centers for Disease Control and Prevention. Not registered.

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对肌肉萎缩症患者睡眠评估、睡眠障碍和治疗频率的系统回顾。

目的：回顾有关肌肉萎缩症患者睡眠障碍频率和接受睡眠相关保健的文献。方法：包括人群- duchenne /Becker （DBMD）、先天性（CMD）、面肩肱（FSHD）、肢带（LGMD）或肌强直性（DM）肌营养不良症；结果-睡眠评估、障碍或治疗的频率；语言英语;研究类型：原创性研究，系统综述。信息来源：PubMed和EBSCO，最后检索日期：2023年3月7日。偏倚风险评估：针对或反对睡眠症状或障碍选择的招募来源或研究纳入。综合：结果的范围和加权平均值（仅限低风险研究）。结果：我们纳入了95项关于睡眠评估(7)、睡眠障碍（94）或睡眠治疗（13）的研究，共有7,964名参与者。对DM-61、DBMD-20、FSHD-9、CMD-1、LGMD-1和多个MD-3的研究报道。一半的DBMD患者（51%，2项研究，85人）和超过60%的DM1患者（65%，2项研究，327人）进行了睡眠研究。通过问卷调查，糖尿病成年人白天过度嗜睡频率为39% （DM2, 10,284）至65%（任何糖尿病，6,1195），对照组为9%(5,199)，其他糖尿病患者为6%至13%。睡眠呼吸暂停频率为11% (LGMD, 1,18) ~ 65% （CMD, 1,20）。辅助通气使用率为5%-16% （DM）。结论：定期的睡眠评估可以改善睡眠障碍的识别和治疗，改善医学患者的身心健康。其他：资助-美国疾病控制与预防中心。没有注册。

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来源期刊

Journal of Clinical Sleep Medicine CLINICAL NEUROLOGY-

CiteScore

6.20

自引率

7.00%

发文量

321

审稿时长

1 months

期刊介绍： Journal of Clinical Sleep Medicine focuses on clinical sleep medicine. Its emphasis is publication of papers with direct applicability and/or relevance to the clinical practice of sleep medicine. This includes clinical trials, clinical reviews, clinical commentary and debate, medical economic/practice perspectives, case series and novel/interesting case reports. In addition, the journal will publish proceedings from conferences, workshops and symposia sponsored by the American Academy of Sleep Medicine or other organizations related to improving the practice of sleep medicine.