{"title":"[Research progress on the relationship between <i>Porphyromonas gingivalis</i> and the pathogenesis of Parkinson disease].","authors":"Y Z Chen, L L Chen, L H Lei","doi":"10.3760/cma.j.cn112144-20251201-00479","DOIUrl":null,"url":null,"abstract":"<p><p><i>Porphyromonas gingivalis</i>, a keystone pathogen in periodontitis, has been confirmed to be associated with various systemic diseases. In recent years, increasing attention has been paid to the link between <i>Porphyromonas gingivalis</i> and neurodegenerative disorders. However, researches on its association with Parkinson disease still lack a systematic review. Starting from the epidemiological evidence connecting <i>Porphyromonas gingivalis</i> and Parkinson disease, this research reviews their clinical and pathological correlations, along with potential underlying mechanisms, aiming to provide insights for further exploration of its pathogenesis and future prevention or treatment strategies.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"61 10","pages":"1536-1541"},"PeriodicalIF":0.0000,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华口腔医学杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/cma.j.cn112144-20251201-00479","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Porphyromonas gingivalis, a keystone pathogen in periodontitis, has been confirmed to be associated with various systemic diseases. In recent years, increasing attention has been paid to the link between Porphyromonas gingivalis and neurodegenerative disorders. However, researches on its association with Parkinson disease still lack a systematic review. Starting from the epidemiological evidence connecting Porphyromonas gingivalis and Parkinson disease, this research reviews their clinical and pathological correlations, along with potential underlying mechanisms, aiming to provide insights for further exploration of its pathogenesis and future prevention or treatment strategies.
期刊介绍:
Founded in August 1953, Chinese Journal of Stomatology is a monthly academic journal of stomatology published publicly at home and abroad, sponsored by the Chinese Medical Association and co-sponsored by the Chinese Stomatology Association. It mainly reports the leading scientific research results and clinical diagnosis and treatment experience in the field of oral medicine, as well as the basic theoretical research that has a guiding role in oral clinical practice and is closely combined with oral clinical practice.
Chinese Journal of Over the years, Stomatology has been published in Medline, Scopus database, Toxicology Abstracts Database, Chemical Abstracts Database, American Cancer database, Russian Abstracts database, China Core Journal of Science and Technology, Peking University Core Journal, CSCD and other more than 20 important journals at home and abroad Physical medicine database and retrieval system included.