Aldana Ayelén Assad, Ricardo Gastón Britos Fodor, Mariana Virginia Teberobsky, Gabriela Laura Arena
{"title":"[Reactional episodes in lepromatous leprosy: presentation of a clinical case]","authors":"Aldana Ayelén Assad, Ricardo Gastón Britos Fodor, Mariana Virginia Teberobsky, Gabriela Laura Arena","doi":"10.31053/1853.0605.v83.n3.49582","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>to present a case of lepromatous leprosy with two reactional episodes during its course.</p><p><strong>Clinical case: </strong>32-year-old woman from Paraguay, who presented with retiform purpura followed by ulceration on the lower limbs, associated with altered thermal and pain sensitivity. She also had skin infiltration, malar region nodules, madarosis, and a saddle nose. The diagnosis of Lucio’s phenomenon in lepromatous leprosy was made through biopsy for histopathology and bacilloscopy. She began treatment with glucocorticoids and antimicrobials according to the WHO regimen, and subsequently developed an upgrading episode with worsening of previous lesions.</p><p><strong>Conclusion: </strong>To highlight the importance of recognizing reactional episodes in order to initiate timely treatment and thus prevent severe disabling complications.</p>","PeriodicalId":38814,"journal":{"name":"Revista de la Facultad de Ciencias Medicas de Cordoba","volume":"83 3","pages":"e49582"},"PeriodicalIF":0.0000,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13701011/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista de la Facultad de Ciencias Medicas de Cordoba","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31053/1853.0605.v83.n3.49582","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: to present a case of lepromatous leprosy with two reactional episodes during its course.
Clinical case: 32-year-old woman from Paraguay, who presented with retiform purpura followed by ulceration on the lower limbs, associated with altered thermal and pain sensitivity. She also had skin infiltration, malar region nodules, madarosis, and a saddle nose. The diagnosis of Lucio’s phenomenon in lepromatous leprosy was made through biopsy for histopathology and bacilloscopy. She began treatment with glucocorticoids and antimicrobials according to the WHO regimen, and subsequently developed an upgrading episode with worsening of previous lesions.
Conclusion: To highlight the importance of recognizing reactional episodes in order to initiate timely treatment and thus prevent severe disabling complications.
期刊介绍:
The Journal of the Faculty of Medical Sciences is a scientific publication of the Secretariat of Science and Technology of the Faculty of Medical Sciences of the National University of Cordoba. Its objective is to disseminate and promote research work related to Medical and Biological Sciences. It publishes scientific works of national and international professionals on different topics related to health sciences from the field of medicine, nursing, kinesiology, diagnostic imaging, phonoaudiology, nutrition, public health, chemical sciences, dentistry and related.