{"title":"Assessing model error in counterfactual worlds.","authors":"Emily Howerton, Justin Lessler","doi":"10.1098/rsif.2025.1176","DOIUrl":null,"url":null,"abstract":"<p><p>Counterfactual scenario modelling exercises that ask 'what would happen if?' are one of the most common ways we plan for the future. Despite their ubiquity in planning and decision-making, scenario projections are rarely evaluated retrospectively. Differences between projections and observations come from two sources: scenario deviation and model miscalibration. We argue the latter is most important for assessing the value of models in decision-making, but requires estimating model error in counterfactual worlds. Here, we present and contrast the theory underlying three approaches for estimating this error, which are possible when observations can inform alternative models of scenario assumptions. We use a simulation experiment to demonstrate the benefits and limitations of each under favourable conditions. Our results illustrate the conditions under which counterfactual errors can be estimated in order to evaluate scenario projections. We further outline how scenarios can be designed to maximize evaluability. This work can serve as the basis for further explorations into scenario evaluation under a variety of conditions using simulation studies and real-world application.</p>","PeriodicalId":17488,"journal":{"name":"Journal of The Royal Society Interface","volume":"23 242","pages":""},"PeriodicalIF":3.4000,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of The Royal Society Interface","FirstCategoryId":"103","ListUrlMain":"https://doi.org/10.1098/rsif.2025.1176","RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Counterfactual scenario modelling exercises that ask 'what would happen if?' are one of the most common ways we plan for the future. Despite their ubiquity in planning and decision-making, scenario projections are rarely evaluated retrospectively. Differences between projections and observations come from two sources: scenario deviation and model miscalibration. We argue the latter is most important for assessing the value of models in decision-making, but requires estimating model error in counterfactual worlds. Here, we present and contrast the theory underlying three approaches for estimating this error, which are possible when observations can inform alternative models of scenario assumptions. We use a simulation experiment to demonstrate the benefits and limitations of each under favourable conditions. Our results illustrate the conditions under which counterfactual errors can be estimated in order to evaluate scenario projections. We further outline how scenarios can be designed to maximize evaluability. This work can serve as the basis for further explorations into scenario evaluation under a variety of conditions using simulation studies and real-world application.
期刊介绍:
J. R. Soc. Interface welcomes articles of high quality research at the interface of the physical and life sciences. It provides a high-quality forum to publish rapidly and interact across this boundary in two main ways: J. R. Soc. Interface publishes research applying chemistry, engineering, materials science, mathematics and physics to the biological and medical sciences; it also highlights discoveries in the life sciences of relevance to the physical sciences. Both sides of the interface are considered equally and it is one of the only journals to cover this exciting new territory. J. R. Soc. Interface welcomes contributions on a diverse range of topics, including but not limited to; biocomplexity, bioengineering, bioinformatics, biomaterials, biomechanics, bionanoscience, biophysics, chemical biology, computer science (as applied to the life sciences), medical physics, synthetic biology, systems biology, theoretical biology and tissue engineering.