{"title":"When the Number Matters: Contextualising Australian Reference Values for <sup>99</sup>ᵐTc-Pertechnetate Thyroid Uptake.","authors":"Geoffrey Schembri, Jeremy Hoang","doi":"10.1002/jmrs.70129","DOIUrl":null,"url":null,"abstract":"<p><p>Are the historical 1%-4% thyroid uptake reference values still valid in modern practice? This editorial examines why contemporary Australian and international data suggest otherwise and situates the new reference range reported by Wornes (https://doi.org/10.1002/jmrs.70078) and colleagues within the broader international literature. It further identifies the one clinical scenario-distinguishing mild Graves' disease from silent thyroiditis-where quantitative uptake measurement genuinely changes management and argues for a nationally coordinated, prospectively designed re-derivation study.</p>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":" ","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13625149/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Radiation Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/jmrs.70129","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Are the historical 1%-4% thyroid uptake reference values still valid in modern practice? This editorial examines why contemporary Australian and international data suggest otherwise and situates the new reference range reported by Wornes (https://doi.org/10.1002/jmrs.70078) and colleagues within the broader international literature. It further identifies the one clinical scenario-distinguishing mild Graves' disease from silent thyroiditis-where quantitative uptake measurement genuinely changes management and argues for a nationally coordinated, prospectively designed re-derivation study.
期刊介绍:
Journal of Medical Radiation Sciences (JMRS) is an international and multidisciplinary peer-reviewed journal that accepts manuscripts related to medical imaging / diagnostic radiography, radiation therapy, nuclear medicine, medical ultrasound / sonography, and the complementary disciplines of medical physics, radiology, radiation oncology, nursing, psychology and sociology. Manuscripts may take the form of: original articles, review articles, commentary articles, technical evaluations, case series and case studies. JMRS promotes excellence in international medical radiation science by the publication of contemporary and advanced research that encourages the adoption of the best clinical, scientific and educational practices in international communities. JMRS is the official professional journal of the Australian Society of Medical Imaging and Radiation Therapy (ASMIRT) and the New Zealand Institute of Medical Radiation Technology (NZIMRT).