Same-day discharge after duodenal endoscopic submucosal dissection and hybrid endoscopic submucosal dissection: a case series of 10 patients

iGIE Pub Date : 2026-09-01 Epub Date: 2026-02-02 DOI:10.1016/j.igie.2026.01.013

Sayaka Nagao MD, PhD, Makoto Nishimura MD, Monika Laszkowska MD, Mako Koseki MD, Laura Tang MD, PhD, Mark A. Schattner MD

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Abstract

Background and Aims

Duodenal endoscopic submucosal dissection (ESD) involves postprocedural hospitalization owing to concerns about delayed adverse events. The safety of same-day discharge (SDD) after duodenal ESD remains unexplored. This case series reports clinical outcomes of patients undergoing SDD after duodenal ESD.

Methods

This case series included 10 patients receiving SDD after duodenal ESD at a tertiary referral center.

Results

Ten patients (5 males) with a mean (standard deviation) age of 62.6 (12.4) years were included. Mean resection size and procedure time were 12.5 (4.5) mm and 66.5 (32.3) minutes, respectively. Complete mucosal defect closure was achieved using endoscopic clips in all patients. No intraoperative or delayed adverse events were observed.

Conclusions

SDD appears safe in carefully selected patients with small lesions undergoing duodenal ESD by experienced endoscopists. These findings provide initial evidence supporting the consideration of SDD after duodenal ESD, although larger studies are needed to establish standardized protocols.

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十二指肠内镜粘膜下剥离及混合内镜粘膜下剥离术后同日出院：10例病例系列

背景和目的十二指肠内镜粘膜下剥离术（ESD）涉及术后住院治疗，因为担心延迟的不良事件。十二指肠ESD术后当日出院（SDD）的安全性尚不明确。本病例系列报告了十二指肠ESD后接受SDD的患者的临床结果。方法本研究包括10例在三级转诊中心接受十二指肠ESD术后SDD的患者。结果纳入患者10例，男性5例，平均（标准差）年龄62.6（12.4）岁。平均切除大小和手术时间分别为12.5 (4.5)mm和66.5（32.3）分钟。所有患者均采用内镜夹完成粘膜缺损闭合。未观察到术中或延迟的不良事件。结论在经验丰富的内镜医师精心挑选的十二指肠ESD小病变患者中，ssdd是安全的。这些发现为十二指肠ESD后考虑SDD提供了初步证据，尽管需要更大规模的研究来建立标准化的方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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iGIE

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