Marcelo Klotz Dall'Agnol MD, Igor Mendonça Proença MSc, Mateus Pereira Funari PhD, Diogo Turiani Hourneaux de Moura PhD, Fernando da Costa Ferreira Novo MD, Fauze Maluf-Filho PhD
{"title":"Successful endoscopic vacuum therapy in diffuse gastric hemorrhage secondary to acute ischemia: a case report","authors":"Marcelo Klotz Dall'Agnol MD, Igor Mendonça Proença MSc, Mateus Pereira Funari PhD, Diogo Turiani Hourneaux de Moura PhD, Fernando da Costa Ferreira Novo MD, Fauze Maluf-Filho PhD","doi":"10.1016/j.igie.2025.10.001","DOIUrl":null,"url":null,"abstract":"<div><div>Acute gastric ischemia is rare and may lead to diffuse mucosal bleeding, often refractory to conventional endoscopic therapy. We describe the case of a 42-year-old critically ill burn patient who developed persistent upper gastrointestinal hemorrhage unresponsive to medical treatment, in whom the novel use of endoscopic vacuum therapy (EVT) was undertaken. Serial endoscopies demonstrated progressive mucosal healing, reduced necrosis, and effective bleeding control. EVT promoted granulation tissue and ulcer healing, avoiding surgical intervention. No EVT-related adverse events occurred. Despite successful hemostasis, the patient later died from a sepsis-related adverse event. In conclusion, this case illustrates EVT as a viable and effective approach for managing refractory diffuse gastric bleeding secondary to ischemia. EVT may offer a minimally invasive alternative to surgery in critically ill patients where standard therapies fail.</div></div>","PeriodicalId":100652,"journal":{"name":"iGIE","volume":"5 3","pages":"Pages 388-392"},"PeriodicalIF":0.0000,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"iGIE","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S294970862500130X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/10/11 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Acute gastric ischemia is rare and may lead to diffuse mucosal bleeding, often refractory to conventional endoscopic therapy. We describe the case of a 42-year-old critically ill burn patient who developed persistent upper gastrointestinal hemorrhage unresponsive to medical treatment, in whom the novel use of endoscopic vacuum therapy (EVT) was undertaken. Serial endoscopies demonstrated progressive mucosal healing, reduced necrosis, and effective bleeding control. EVT promoted granulation tissue and ulcer healing, avoiding surgical intervention. No EVT-related adverse events occurred. Despite successful hemostasis, the patient later died from a sepsis-related adverse event. In conclusion, this case illustrates EVT as a viable and effective approach for managing refractory diffuse gastric bleeding secondary to ischemia. EVT may offer a minimally invasive alternative to surgery in critically ill patients where standard therapies fail.