Acute Effects of Brief Exercise on Alcohol Craving Among Young Adults With Problematic Alcohol Use: A Systematic Review

IF 3
P. Sampedro-Piquero, A. Cordellat-Marzal, M. Dragotti, L. Mandolesi, O. Gigliotta, R. D. Moreno-Fernández
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Abstract

Alcohol craving is a key process in alcohol abuse, especially during young adulthood, a period of heightened vulnerability and continued brain development. Although acute physical exercise has been proposed as a potential strategy to reduce craving and modulate affective and cognitive processes, current evidence remains limited regarding its effectiveness and underlying mechanisms. This systematic review examined the effects of brief exercise interventions on alcohol craving in young adults with problematic alcohol use or alcohol use disorder (AUD) and explored available evidence on associated neurobiological responses. Four electronic databases were searched for studies published between 2016 and 2026 following PRISMA guidelines. The review protocol was registered in PROSPERO (CRD420261371036). Eligible studies included participants aged 18–29 years and assessed alcohol craving following a single bout of exercise. Random-effects meta-analyses using Hedges' g were conducted when sufficient data were available, while additional outcomes were synthesized narratively. Six studies met the inclusion criteria. Meta-analysis showed a moderate and statistically significant reduction in alcohol craving following acute exercise compared with baseline or control conditions (g ≈ 0.55), with moderate between-study heterogeneity. Narrative findings indicated that acute exercise was often accompanied by reductions in anxiety and negative affective state, modulation of stress-related physiological markers, improvements in executive functioning, and changes in indices of brain and autonomic activity, although findings varied across studies. Overall, available evidence suggests that a single session of physical exercise may be associated with short-term reductions in alcohol craving in young adults, highlighting the need for further clinically focused and methodologically robust research.

短期运动对有问题酒精使用的年轻人酒精渴望的急性影响:一项系统综述。
对酒精的渴望是酒精滥用的一个关键过程,尤其是在年轻的成年期,这是一个高度脆弱和大脑持续发育的时期。尽管急性体育锻炼被认为是一种减少渴望和调节情感和认知过程的潜在策略,但目前关于其有效性和潜在机制的证据仍然有限。本系统综述研究了短期运动干预对有问题酒精使用或酒精使用障碍(AUD)的年轻人的酒精渴望的影响,并探讨了相关神经生物学反应的现有证据。在四个电子数据库中检索了2016年至2026年期间根据PRISMA指南发表的研究。该审查方案已在PROSPERO注册(CRD420261371036)。符合条件的研究包括18-29岁的参与者,并在一次运动后评估酒精渴望。当有足够的数据可用时,使用Hedges' g进行随机效应荟萃分析,而其他结果则以叙述方式合成。6项研究符合纳入标准。荟萃分析显示,与基线或对照组相比,急性运动后酒精渴望有中度和统计学意义上的显著减少(g≈0.55),研究间存在中度异质性。叙述性研究结果表明,急性运动通常伴随着焦虑和消极情感状态的减少,与压力相关的生理指标的调节,执行功能的改善,以及大脑和自主神经活动指数的变化,尽管研究结果各不相同。总的来说,现有证据表明,一次体育锻炼可能与年轻人短期内对酒精的渴望减少有关,这突出了进一步以临床为重点和方法学上强有力的研究的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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