Breast Cancer-Related Quality of Life among Women Undergoing Treatment: A Hospital-Based Study in Vietnam.

Q2 Medicine

Asian Pacific Journal of Cancer Prevention Pub Date : 2026-09-01 DOI:10.31557/APJCP.2026.27.9.3449

Tuyen Dinh Hoang, Thang Van Vo, Pongdech Sarakarn

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引用次数: 0

Abstract

Background: Despite the rising incidence of breast cancer (BC), survival rates have improved due to advancements in early detection and treatment. With longer survival, it is increasingly important to evaluate and enhance patients' quality of life (QoL), particularly the functional and symptom-related aspects of BC. This study aims to assess BC-related QoL and its associated factors among women undergoing treatment.

Method: A hospital-based cross-sectional study assessed BC-related QoL in 284 patients using the European Organization for Research and Treatment of Cancer (EORTC) QoL Questionnaire for BC (QLQ-BR45) between March 10 and May 14, 2025. Statistical analyses included multivariable linear regression to identify factors associated with 12 domains of patient QoL.

Results: QoL findings showed high body image scores (72.51) but low sexual functioning (13.50) and sexual enjoyment (26.29), with hair-loss distress (51.32) and systemic therapy side effects (30.92) being the most burdensome symptoms. Older age and higher body mass index (BMI) had both positive and negative associations with QoL, while marriage, higher education, urban residence, and longer breastfeeding were linked to better outcomes. Late-stage disease, older age at first childbirth, and receiving no treatment were linked to poorer outcomes. Treatment had varying effects on QoL domains: surgery plus chemotherapy improved sexual enjoyment, while non-surgical approaches alleviated symptoms across several QoL-related domains.

Conclusion: BC patients showed strong body image but poor sexual functioning and notable symptom burdens, underscoring the need for supportive care that addresses physical and psychosocial issues. Routine QoL monitoring and broader multicenter studies are essential to guide tailored interventions and improve overall patient QoL.

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接受治疗的妇女乳腺癌相关生活质量：越南一项基于医院的研究

背景：尽管乳腺癌（BC）的发病率不断上升，但由于早期发现和治疗的进步，生存率有所提高。随着生存期的延长，评估和提高患者的生活质量（QoL），特别是BC的功能和症状相关方面变得越来越重要。本研究旨在评估接受治疗的女性bc相关生活质量及其相关因素。方法：在2025年3月10日至5月14日期间，采用欧洲癌症研究与治疗组织（EORTC） BC生活质量问卷（QLQ-BR45）对284例患者的BC相关生活质量进行了基于医院的横断面研究。统计分析包括多变量线性回归，以确定与患者生活质量的12个领域相关的因素。结果：生活质量表现为身体形象得分高（72.51分），性功能得分低（13.50分），性享受得分低（26.29分），其中脱发困扰（51.32分）和全身治疗副作用（30.92分）是患者最沉重的症状。年龄较大和较高的身体质量指数（BMI）与生活质量既有正相关，也有负相关，而婚姻、高等教育、城市居住和更长时间的母乳喂养与更好的结果有关。疾病晚期、初次分娩年龄较大以及未接受治疗与较差的结果有关。治疗对生活质量领域有不同的影响：手术加化疗改善了性享受，而非手术方法缓解了几个生活质量相关领域的症状。结论：BC患者表现出强烈的身体形象，但性功能差，症状负担明显，强调需要解决身体和社会心理问题的支持性护理。常规的生活质量监测和更广泛的多中心研究对于指导量身定制的干预措施和改善患者的总体生活质量至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Asian Pacific Journal of Cancer Prevention 医学-肿瘤学

CiteScore

2.80

自引率

0.00%

发文量

779

审稿时长

3 months

期刊介绍： Cancer is a very complex disease. While many aspects of carcinoge-nesis and oncogenesis are known, cancer control and prevention at the community level is however still in its infancy. Much more work needs to be done and many more steps need to be taken before effective strategies are developed. The multidisciplinary approaches and efforts to understand and control cancer in an effective and efficient manner, require highly trained scientists in all branches of the cancer sciences, from cellular and molecular aspects to patient care and palliation. The Asia Pacific Organization for Cancer Prevention (APOCP) and its official publication, the Asia Pacific Journal of Cancer Prevention (APJCP), have served the community of cancer scientists very well and intends to continue to serve in this capacity to the best of its abilities. One of the objectives of the APOCP is to provide all relevant and current scientific information on the whole spectrum of cancer sciences. They aim to do this by providing a forum for communication and propagation of original and innovative research findings that have relevance to understanding the etiology, progression, treatment, and survival of patients, through their journal. The APJCP with its distinguished, diverse, and Asia-wide team of editors, reviewers, and readers, ensure the highest standards of research communication within the cancer sciences community across Asia as well as globally. The APJCP publishes original research results under the following categories: -Epidemiology, detection and screening. -Cellular research and bio-markers. -Identification of bio-targets and agents with novel mechanisms of action. -Optimal clinical use of existing anti-cancer agents, including combination therapies. -Radiation and surgery. -Palliative care. -Patient adherence, quality of life, satisfaction. -Health economic evaluations.