Angela Zhu, Jingyi Cheng, James Fiori, Rajiv Kurup, Daniel Ng, Faris Gondal, Andrew Brett
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引用次数: 0
Abstract
Gastrointestinal manifestations of light chain deposition disease are exceedingly rare and are characterized by gastrointestinal bleeding, nutritional deficiencies and protein-losing enteropathy. Diagnosis is challenging due to nonspecific symptomatology and indolent disease progression. We describe the case of a 69-year-old woman presenting with melena, chronic diarrhea, and recurrent sepsis. Gastroscopy revealed a highly unusual snakeskin appearance of the duodenum, with histopathology and immunofluorescence confirming light chain deposition disease. This case highlights the importance of prompt biopsy acquisition, hematological evaluation and assessment of extragastrointestinal involvement in facilitating a timely diagnosis, particularly when an underlying lymphoplasmacytic lymphoma is a possible driver of disease.
期刊介绍：
ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.
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