Mixed Neuroendocrine Carcinoma and Adenocarcinoma in a Patient With Ileal Pouch-Anal Anastomosis.

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY

ACG Case Reports Journal Pub Date : 2026-09-28 eCollection Date: 2026-10-01 DOI:10.14309/crj.0000000000002342

Prajith Raj Ramesh, Victor Chedid, Siri A Urquhart

引用次数: 0

Abstract

Neoplasia of the ileoanal pouch is uncommon, occurring in fewer than 1% of patients. Neuroendocrine carcinoma (NEC) is a rare neoplastic complication and can be difficult to diagnose due to symptoms overlapping with inflammatory pouch disorders. We describe a 36-year-old man with ileal pouch-anal anastomosis complicated by Crohn's-like disease of the pouch who underwent pouch excision for refractory disease. Histopathology revealed mixed poorly differentiated adenocarcinoma and NEC. Management may involve surgical resection for localized disease and systemic therapy for advanced stages. This case highlights the need to consider neoplastic processes, including NECs, in patients with persistent or atypical pouch symptoms.

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回肠袋肛吻合术并发神经内分泌癌和腺癌1例。

回肠袋瘤变并不常见，发生率不到1%。神经内分泌癌（NEC）是一种罕见的肿瘤并发症，由于其症状与炎性眼袋疾病重叠而难以诊断。我们描述了一个36岁的男性回肠袋-肛门吻合术并发克罗恩病的眼袋谁接受眼袋切除难治性疾病。组织病理学显示混合性低分化腺癌和NEC。治疗可能包括局部疾病的手术切除和晚期的全身治疗。本病例强调在持续或非典型眼袋症状的患者中需要考虑肿瘤进程，包括NECs。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.