Torpedo Maculopathy Complicated by Macular Neovascularization and Secondary Multiple Evanescent White Dot Syndrome.

IF 1.7 4区医学 Q2 OPHTHALMOLOGY

Ocular Immunology and Inflammation Pub Date : 2026-09-27 DOI:10.1080/09273948.2026.2736172

Alexandre Barbé, Sarah Mrejen, Diana Bratu, Francesc March de Ribot, Nathalie Massamba, Christine Fardeau, Bahram Bodaghi, Sara Touhami

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引用次数: 0

Abstract

Purpose: To report a case of torpedo maculopathy complicated by choroidal neovascularization (CNV) followed by secondary multiple evanescent white dot syndrome (MEWDS).

Methods: Case report.

Results: A 28-year-old male was referred for acute vision loss in his right eye. Fundus examination revealed a torpedo-shaped lesion temporal to the fovea. Optical coherence tomography (OCT) revealed a pigment epithelium detachment (PED) with overlying subretinal hyper-reflective material (SHRM), flow signal on OCT-angiography as well as hyper fluorescence on fluorescein angiography, consistent with CNV. More peripheral to the macula, indocyanine green angiography revealed multiple late-phase hypo fluorescent spots being hyper-autofluorescent on fundus autofluorescence and exhibiting ellipsoid zone disruption on OCT, supporting the diagnosis of secondary MEWDS.

Conclusion: This is the first reported case of torpedo maculopathy complicated by both CNV and MEWDS. This case study exemplifies how congenital macular anomalies can progress to neovascular and inflammatory complications.

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鱼雷型黄斑病变并发黄斑新生血管和继发性多发消失性白点综合征。

目的：报告一例鱼雷性黄斑病变并发脉络膜新生血管（CNV），继发多发性消失性白点综合征（MEWDS）。方法：病例报告。结果：一名28岁男性因右眼急性视力丧失而被转诊。眼底检查显示颞部至中央窝有一鱼雷状病变。光学相干断层扫描（OCT）显示色素上皮脱离（PED），视网膜下超反射物质（SHRM）覆盖，OCT血管造影显示血流信号，荧光素血管造影显示高荧光，与CNV一致。在黄斑周围，吲哚菁绿血管造影显示多个晚期低荧光斑点，在眼底自身荧光上表现为超自荧光，在OCT上表现为椭球区破坏，支持继发性MEWDS的诊断。结论：这是首例鱼雷性黄斑病变合并CNV和MEWDS的病例报道。本病例研究举例说明先天性黄斑异常如何发展为新的血管和炎症并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ocular Immunology and Inflammation 医学-眼科学

CiteScore

6.20

自引率

15.20%

发文量

285

审稿时长

6-12 weeks

期刊介绍： Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.