Design of Dual-Path Antibacterial Aluminum Alloy Based on ZnO Sputtering and Surface Roughness Control

IF 5.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
ACS Applied Bio Materials Pub Date : 2026-10-19 Epub Date: 2026-09-27 DOI:10.1021/acsabm.6c01369
Xia Luo, Zijun Liu, Yaqun Yao, Jia Meng, Kunfu Zhu, Huiwei Feng, Feng Xue, Yanyan Jiang
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引用次数: 0

Abstract

Antibacterial alloys based on aluminum alloys have become a hot topic. However, most existing research is limited to a single antibacterial mechanism and may suffer from insufficient long-term efficacy, making it difficult to meet the requirements of large-scale production and applications in diverse scenarios. Therefore, the development of a synergistic, multi-mechanism antibacterial modification strategy for aluminum alloys is urgently needed. In this study, a dual-mechanism antibacterial aluminum alloy was developed by combining surface-structure-assisted antibacterial activity with ZnO-mediated antibacterial activity. By adjusting various process parameters, the surface roughness of the aluminum alloy and the microstructure of ZnO were regulated. This study systematically investigated the effects of aluminum-alloy surface roughness and ZnO microstructure on the antibacterial performance of the composite system. In vitro antibacterial test results showed that aluminum alloy subjected to the dual-mechanism modification exhibited excellent antibacterial activity: the antibacterial rate against E. coli and S. aureus reached 95 and 90%, respectively. This study provides a strategy to construct the dual-pathway synergistic antibacterial aluminum alloy, which possesses great potential in applications such as food processing, medical devices, and public health.

基于ZnO溅射和表面粗糙度控制的双路抗菌铝合金设计。
以铝合金为基材的抗菌合金已成为研究热点。然而,现有的研究大多局限于单一的抗菌机制,长期疗效可能不足,难以满足规模化生产和多种场景应用的要求。因此,迫切需要开发一种协同的、多机理的铝合金抗菌改性策略。本研究将表面结构辅助抗菌活性与zno介导的抗菌活性相结合,开发了一种双机制抗菌铝合金。通过调整各种工艺参数,可以调节铝合金的表面粗糙度和ZnO的显微组织。本研究系统地研究了铝合金表面粗糙度和ZnO微观结构对复合体系抗菌性能的影响。体外抗菌试验结果表明,经双机制修饰的铝合金具有优异的抗菌活性,对大肠杆菌和金黄色葡萄球菌的抑菌率分别达到95%和90%。本研究为构建双途径协同抗菌铝合金提供了一条思路,在食品加工、医疗器械、公共卫生等领域具有巨大的应用潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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