Cross-Sectional Study of the PREValence of Erectile DysfunctIon in the Arteriopathic Population (PREVEDI).

IF 3.4 2区医学 Q1 ANDROLOGY

Andrology Pub Date : 2026-09-26 DOI:10.1111/andr.70406

Luca Farchioni, Andrea Ferri, Nicola Leone, Mattia Migliari, Luigi Alberto Maria Bartolotti, Daniele Santi, Giorgia Spaggiari, Roberto Silingardi, Stefano Gennai

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引用次数: 0

Abstract

Background: Although the association between erectile dysfunction (ED) and cardiovascular disease is well established, its prevalence in patients with atherosclerosis remains poorly defined.

Objectives: To evaluate ED prevalence, severity, and associated risk factors (RFs) in patients with atherosclerotic disease.

Materials and methods: This single-centre, cross-sectional, non-randomised observational study included male patients referred to a vascular surgery service with documented atherosclerotic disease. Erectile function was assessed using the International Index of Erectile Function-15 questionnaire, and RFs were analysed using univariable and multivariable regression models.

Results: A total of 162 patients were enrolled (mean age, 70.1 ± 8.6 years); ED was present in 93.8%, with severe ED observed in 62.3%. Multivariable analysis confirmed age as a significant RF for ED, particularly > 75 years, while age, diabetes mellitus, and subjective ED duration were significantly associated with greater severity.

Discussion: The high prevalence of ED supports its role as a manifestation of systemic vascular disease linked to endothelial dysfunction and diffuse atherosclerosis.

Conclusion: ED is highly prevalent among patients with clinically overt atherosclerotic disease requiring vascular surgery referral, and may represent a marker of systemic vascular pathology. Routine assessment of sexual function may improve cardiovascular risk stratification and preventive management.

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动脉病变人群中勃起功能障碍患病率的横断面研究（PREVEDI）。

背景：虽然勃起功能障碍（ED）与心血管疾病之间的关系已经确立，但其在动脉粥样硬化患者中的患病率仍不明确。目的：评估动脉粥样硬化性疾病患者ED的患病率、严重程度和相关危险因素（RFs）。材料和方法：这项单中心、横断面、非随机的观察性研究纳入了有动脉粥样硬化性疾病的男性患者。使用国际勃起功能指数-15问卷评估勃起功能，并使用单变量和多变量回归模型分析RFs。结果：共纳入162例患者（平均年龄70.1±8.6岁）；ED占93.8%，重度ED占62.3%。多变量分析证实，年龄是ED的重要影响因素，尤其是75岁以上，而年龄、糖尿病和主观ED持续时间与ED的严重程度显著相关。讨论：ED的高患病率支持其作为与内皮功能障碍和弥漫性动脉粥样硬化相关的全身性血管疾病的表现。结论：ED在临床上明显的动脉粥样硬化性疾病需要血管手术转诊的患者中非常普遍，可能是全身性血管病理的标志。常规性功能评估可改善心血管风险分层和预防管理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Andrology ANDROLOGY-

CiteScore

9.10

自引率

6.70%

发文量

200

期刊介绍： Andrology is the study of the male reproductive system and other male gender related health issues. Andrology deals with basic and clinical aspects of the male reproductive system (gonads, endocrine and accessory organs) in all species, including the diagnosis and treatment of medical problems associated with sexual development, infertility, sexual dysfunction, sex hormone action and other urological problems. In medicine, Andrology as a specialty is a recent development, as it had previously been considered a subspecialty of urology or endocrinology