Alisha Kashyap, Alexander J. Jafari, Natasha Klimas, Misha Koshelev, Steven R. Mays, Adelaide A. Hebert
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引用次数: 0
Abstract
Pediatric morphea, also known as localized scleroderma, is a rare autoimmune condition characterized by skin fibrosis and, in severe cases, deeper tissue involvement. This review highlights the epidemiology, clinical presentation, and diagnostic challenges associated with pediatric morphea. The evolving landscape of therapeutic strategies underscores the importance of early intervention, multidisciplinary care, and long-term follow-up to address both physical and psychosocial impacts in children. Future directions, including personalized medicine and standardized outcome metrics, can potentially improve outcomes for pediatric morphea patients. Traditional and emerging treatment options, ranging from topical agents and methotrexate to novel monoclonal antibodies and JAK inhibitors, are discussed.
期刊介绍：
Archives of Dermatological Research is a highly rated international journal that publishes original contributions in the field of experimental dermatology, including papers on biochemistry, morphology and immunology of the skin. The journal is among the few not related to dermatological associations or belonging to respective societies which guarantees complete independence. This English-language journal also offers a platform for review articles in areas of interest for dermatologists and for publication of innovative clinical trials.
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