AI-driven actuation-compatible tracking for closed-loop navigation of miniature robots in vivo

IF 25.5 1区 计算机科学 Q1 ROBOTICS
Delin Hu, Zhaoyang Qi, Yihang Jiang, Xurui Liu, Moqiu Zhang, Haojin Yang, Li Zhang
{"title":"AI-driven actuation-compatible tracking for closed-loop navigation of miniature robots in vivo","authors":"Delin Hu,&nbsp;Zhaoyang Qi,&nbsp;Yihang Jiang,&nbsp;Xurui Liu,&nbsp;Moqiu Zhang,&nbsp;Haojin Yang,&nbsp;Li Zhang","doi":"10.1126/scirobotics.aee0592","DOIUrl":null,"url":null,"abstract":"<div >Miniature wireless magnetic robots (MWMRs) hold immense potential for minimally invasive interventions. Real-time tracking of MWMRs is essential for precise in vivo navigation but remains challenging. Tracking MWMRs via their emitted magnetic signals offers a viable solution, yet it has been limited to centimeter-scale robots because isolating weak MWMR signals from overwhelming actuation-induced interference becomes increasingly difficult with miniaturization. Here, we present an artificial intelligence (AI)–driven tracking system to overcome these challenges, enabling precise localization of millimeter-scale MWMRs in the presence of actuation fields. Our approach integrates a sensor array design with a transformer to accurately model and filter the interference, followed by a spatiotemporal transformer that interprets the extracted MWMR signals over a short time window to corresponding three-dimensional coordinates. Our system has been validated in a range of in vitro and in vivo experiments, demonstrating its applicability to closed-loop navigation of MWMRs in unshielded clinical settings.</div>","PeriodicalId":56029,"journal":{"name":"Science Robotics","volume":"11 118","pages":""},"PeriodicalIF":25.5000,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Science Robotics","FirstCategoryId":"94","ListUrlMain":"https://www.science.org/doi/10.1126/scirobotics.aee0592","RegionNum":1,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ROBOTICS","Score":null,"Total":0}
引用次数: 0

Abstract

Miniature wireless magnetic robots (MWMRs) hold immense potential for minimally invasive interventions. Real-time tracking of MWMRs is essential for precise in vivo navigation but remains challenging. Tracking MWMRs via their emitted magnetic signals offers a viable solution, yet it has been limited to centimeter-scale robots because isolating weak MWMR signals from overwhelming actuation-induced interference becomes increasingly difficult with miniaturization. Here, we present an artificial intelligence (AI)–driven tracking system to overcome these challenges, enabling precise localization of millimeter-scale MWMRs in the presence of actuation fields. Our approach integrates a sensor array design with a transformer to accurately model and filter the interference, followed by a spatiotemporal transformer that interprets the extracted MWMR signals over a short time window to corresponding three-dimensional coordinates. Our system has been validated in a range of in vitro and in vivo experiments, demonstrating its applicability to closed-loop navigation of MWMRs in unshielded clinical settings.
微型机器人体内闭环导航的人工智能驱动驱动兼容跟踪
微型无线磁性机器人(MWMRs)在微创干预方面具有巨大的潜力。mwmr的实时跟踪对于精确的体内导航是必不可少的,但仍然具有挑战性。通过MWMR发射的磁信号跟踪MWMR提供了一个可行的解决方案,但它仅限于厘米级机器人,因为随着小型化,将微弱的MWMR信号与压倒性的驱动诱导干扰隔离开来变得越来越困难。在这里,我们提出了一种人工智能(AI)驱动的跟踪系统来克服这些挑战,在驱动场存在的情况下实现毫米级mwmr的精确定位。我们的方法集成了传感器阵列设计和变压器,以精确建模和过滤干扰,然后是一个时空变压器,在短时间窗口内将提取的MWMR信号解释为相应的三维坐标。我们的系统已在一系列体外和体内实验中得到验证,证明了其在非屏蔽临床环境中对mwmr闭环导航的适用性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Science Robotics
Science Robotics Mathematics-Control and Optimization
CiteScore
30.60
自引率
2.80%
发文量
83
期刊介绍: Science Robotics publishes original, peer-reviewed, science- or engineering-based research articles that advance the field of robotics. The journal also features editor-commissioned Reviews. An international team of academic editors holds Science Robotics articles to the same high-quality standard that is the hallmark of the Science family of journals. Sub-topics include: actuators, advanced materials, artificial Intelligence, autonomous vehicles, bio-inspired design, exoskeletons, fabrication, field robotics, human-robot interaction, humanoids, industrial robotics, kinematics, machine learning, material science, medical technology, motion planning and control, micro- and nano-robotics, multi-robot control, sensors, service robotics, social and ethical issues, soft robotics, and space, planetary and undersea exploration.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书