Development of a Chitosan-Based Wound Dressing from Shrimp Shells Incorporated with Ethanol Extracts of Fruit Peels for Inhibiting Staphylococcus aureus and Staphylococcus epidermidis Infections.

IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL

International Journal of Preventive Medicine Pub Date : 2026-08-28 eCollection Date: 2026-01-01 DOI:10.4103/ijpvm.ijpvm_30_25

Wiraporn Suwanmongkol, Jasanee Ngamplrensin, Bongkosh Auvichien, Sunisa Krainara, Rattiporn Kosuwin, Pakarang Srimee, Pattakorn Buppan

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引用次数: 0

Abstract

Background: Bacterial infections caused by Staphylococcus aureus and Staphylococcus epidermidis continue to pose a significant challenge to global healthcare. To assess its antibacterial efficacy, this study aimed to develop a wound dressing composed of shrimp shell-derived chitosan combined with extracts from fruit peels, specifically tangerine, mangosteen, and banana peel.

Methods: Bioactive compounds were extracted using ethanol, and the minimum inhibitory concentration (MIC) against the bacteria was determined.

Results: Among the extracts tested, mangosteen peel demonstrated the highest efficacy (MIC = 0.39 mg/mL for S. epidermidis) compared to tangerine and banana peels. Evaluation of the developed wound dressings revealed that those containing mangosteen peel extract exhibited the largest bacterial inhibition zones.

Conclusions: These findings highlight the potential of agricultural waste materials to create sustainable and ecofriendly medical products.

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壳聚糖基虾壳复合果皮乙醇提取物抗金黄色葡萄球菌和表皮葡萄球菌感染创面敷料的研制

背景：金黄色葡萄球菌和表皮葡萄球菌引起的细菌感染继续对全球医疗保健构成重大挑战。为了评估其抗菌效果，本研究旨在开发一种由虾壳衍生的壳聚糖与果皮（特别是橘子、山竹和香蕉皮）提取物联合制成的伤口敷料。方法：用乙醇提取活性成分，测定其对细菌的最低抑菌浓度。结果：山竹皮对表皮葡萄球菌的抑制作用最高，MIC = 0.39 mg/mL；对开发的伤口敷料的评价显示，含有山竹皮提取物的伤口敷料具有最大的细菌抑制区。结论：这些发现突出了农业废弃物创造可持续和生态友好型医疗产品的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Preventive Medicine MEDICINE, GENERAL & INTERNAL-

CiteScore

3.20

自引率

4.80%

发文量

107

期刊介绍： International Journal of Preventive Medicine, a publication of Isfahan University of Medical Sciences, is a peer-reviewed online journal with Continuous print on demand compilation of issues published. The journal’s full text is available online at http://www.ijpvmjournal.net. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository. The journal will cover technical and clinical studies related to health, ethical and social issues in field of Preventive Medicine. Articles with clinical interest and implications will be given preference.