The effect of cycloplegia on corneal power and diameter measured by an auto-kerato-refractometer in presbyopic patients with type 2 diabetes mellitus: a post-hoc analysis of a randomized clinical trial.

IF 2.1 4区医学 Q3 OPHTHALMOLOGY

BMC Ophthalmology Pub Date : 2026-09-18 DOI:10.1186/s12886-026-05351-1

Navid Elmi Sadr, Leila Ghiasian, Yasaman Hadi, Ramyar Hariri

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引用次数: 0

Abstract

Background: To assess the effect of cycloplegia on keratometry and horizontal white to white (WTW) measurements in presbyopic patients with type 2 diabetes.

Methods: The post-hoc analysis included 88 eyes from 88 patients with type 2 diabetes aged >40 years. Flat keratometry (Kf), steep keratometry (Ks), mean keratometry (Km), corneal astigmatism (CA), and WTW were measured using the RC-5000 auto kerato-refractometer (Tomey Inc., Nagoya, Japan), before and thirty minutes after the instillation of two drops (administered five minutes apart) of either 0.5% (46 patients) or 1% tropicamide (42 patients).

Results: The mean changes in Kf, Ks, Km, CA, and WTW were - 0.01 ± 0.26 D, -0.05 ± 0.23 D, -0.03 ± 0.19 D, -0.04 ± 0.31 D, and 0.05 ± 0.24 mm, respectively, in the 0.5% tropicamide group. These values were - 0.07 ± 0.28 D, 0.01 ± 0.23 D, -0.03 ± 0.21 D, 0.08 ± 0.29 D, and 0.04 ± 0.15 mm, respectively, in the 1% tropicamide group. The changes following cycloplegia were not statistically significant (P ˃ 0.05).

Conclusions: Post-cycloplegia keratometry and WTW measurements were comparable to pre-cycloplegia values in presbyopic patients with type 2 diabetes, suggesting that these measurements can be reliably obtained after cycloplegia.

Trial registration: IRCT.ir, registration number: IRCT20200829048553N1, 2021-05-31.

Clinicaltrials: gov, ID: NCT04932213, 2021-06-21.

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一项随机临床试验的事后分析：睫状体麻痹对老花眼合并2型糖尿病患者角膜屈光计测量的角膜度数和直径的影响。

背景：评估睫状体麻痹对老花眼合并2型糖尿病患者角膜测量和水平白到白（WTW）测量的影响。方法：事后分析纳入88例年龄在10 ~ 40岁的2型糖尿病患者的88只眼。使用RC-5000自动角膜屈光仪（Tomey Inc., Nagoya, Japan）在滴注0.5%（46例）或1% tropicamide（42例）两滴（间隔5分钟）前和30分钟后，测量平板角膜屈光仪（Kf）、陡角角膜屈光仪（Ks）、平均角膜屈光仪（Km）、角膜散光仪（CA）和WTW。结果：0.5% tropicamide组Kf、Ks、Km、CA、WTW的平均变化分别为- 0.01±0.26 D、-0.05±0.23 D、-0.03±0.19 D、-0.04±0.31 D、0.05±0.24 mm。1% tropicamide组分别为- 0.07±0.28 D、0.01±0.23 D、-0.03±0.21 D、0.08±0.29 D、0.04±0.15 mm。单眼截瘫后的变化无统计学意义（P > 0.05）。结论：在老花眼合并2型糖尿病患者中，睫状体麻痹后的角膜测量和WTW测量值与睫状体麻痹前的值相当，表明这些测量值可以在睫状体麻痹后可靠地获得。试验注册：IRCT。注册号：IRCT20200829048553N1, 20121-05-31。Clinicaltrials: gov, ID: NCT04932213, 20121-06-21。

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来源期刊

BMC Ophthalmology OPHTHALMOLOGY-

CiteScore

3.40

自引率

5.00%

发文量

441

审稿时长

6-12 weeks

期刊介绍： BMC Ophthalmology is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of eye disorders, as well as related molecular genetics, pathophysiology, and epidemiology.