{"title":"Concurrent Intestinal Tuberculosis and Colon Cancer in a Young Patient: A Diagnostic Challenge.","authors":"Anusha A, Ratnakar Kini, Prem Kumar Karunakaran","doi":"10.14309/crj.0000000000002299","DOIUrl":null,"url":null,"abstract":"<p><p>Concurrent intestinal tuberculosis and colonic adenocarcinoma are rare and pose significant diagnostic challenges due to overlapping clinical and endoscopic features. We report a 25-year-old woman presenting with right iliac fossa pain, anorexia, and 10-kg weight loss. Colonoscopy showed a proliferative ascending colon growth with adjacent cecal ulcers. Histopathology confirmed adenocarcinoma from the growth, while catridge-based nucleic acid amplification test from the ulcers detected <i>Mycobacterium tuberculosis</i>. The patient received antitubercular therapy, followed by right hemicolectomy and adjuvant folinic acid, 5-fluorouracil, and oxaliplatin chemotherapy. This case emphasizes the importance of obtaining separate biopsies from multiple lesions to identify dual pathology and ensure appropriate sequential management in tuberculosis-endemic regions.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 9","pages":"e02299"},"PeriodicalIF":0.6000,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13593144/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACG Case Reports Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14309/crj.0000000000002299","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/9/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Concurrent intestinal tuberculosis and colonic adenocarcinoma are rare and pose significant diagnostic challenges due to overlapping clinical and endoscopic features. We report a 25-year-old woman presenting with right iliac fossa pain, anorexia, and 10-kg weight loss. Colonoscopy showed a proliferative ascending colon growth with adjacent cecal ulcers. Histopathology confirmed adenocarcinoma from the growth, while catridge-based nucleic acid amplification test from the ulcers detected Mycobacterium tuberculosis. The patient received antitubercular therapy, followed by right hemicolectomy and adjuvant folinic acid, 5-fluorouracil, and oxaliplatin chemotherapy. This case emphasizes the importance of obtaining separate biopsies from multiple lesions to identify dual pathology and ensure appropriate sequential management in tuberculosis-endemic regions.
期刊介绍：
ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.
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