{"title":"Percentile charts for eGFR.","authors":"Arne Åsberg, Øyvind Skadberg","doi":"10.1080/00365513.2026.2727994","DOIUrl":null,"url":null,"abstract":"<p><p>Estimated glomerular filtration rate (eGFR) serves as an overall indicator of kidney health. A sustained value below 60 mL/min/1.73 m<sup>2</sup> for more than 3 months confirms a diagnosis of chronic kidney disease. The same decision limit is used for patients at all ages. This may not be ideal, however, because eGFR decreases with age in healthy individuals above 40 years of age. Evidence suggests that percentile charts for eGFR could have clinical value. We used a so-called indirect method with production data to construct percentiles of serum creatinine levels in healthy white Europeans aged 2 to 84 years. These percentiles were converted into eGFR values to construct percentile charts for the European eGFR<sub>EKFC</sub>. Between ages 20 and 84, our curves differ somewhat from a recent study of healthy European adults, whereas the curves for ages 6-12 align more closely with a recent study of healthy European children.</p>","PeriodicalId":21474,"journal":{"name":"Scandinavian Journal of Clinical & Laboratory Investigation","volume":" ","pages":"621-626"},"PeriodicalIF":1.4000,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scandinavian Journal of Clinical & Laboratory Investigation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/00365513.2026.2727994","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/9/21 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
Abstract
Estimated glomerular filtration rate (eGFR) serves as an overall indicator of kidney health. A sustained value below 60 mL/min/1.73 m2 for more than 3 months confirms a diagnosis of chronic kidney disease. The same decision limit is used for patients at all ages. This may not be ideal, however, because eGFR decreases with age in healthy individuals above 40 years of age. Evidence suggests that percentile charts for eGFR could have clinical value. We used a so-called indirect method with production data to construct percentiles of serum creatinine levels in healthy white Europeans aged 2 to 84 years. These percentiles were converted into eGFR values to construct percentile charts for the European eGFREKFC. Between ages 20 and 84, our curves differ somewhat from a recent study of healthy European adults, whereas the curves for ages 6-12 align more closely with a recent study of healthy European children.
期刊介绍：
The Scandinavian Journal of Clinical and Laboratory Investigation is an international scientific journal covering clinically oriented biochemical and physiological research. Since the launch of the journal in 1949, it has been a forum for international laboratory medicine, closely related to, and edited by, The Scandinavian Society for Clinical Chemistry.
The journal contains peer-reviewed articles, editorials, invited reviews, and short technical notes, as well as several supplements each year. Supplements consist of monographs, and symposium and congress reports covering subjects within clinical chemistry and clinical physiology.
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