Comparative analysis of different modifications of the Caprini risk score in bariatric surgery.

IF 1.5
Alexander G Khitaryan, Alexey A Orekhov, Elena Y Kirtanasova, Vladislav P Evdokimov, Valeriya V Kozlova, Kirill V Lobastov
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Abstract

BackgroundBariatric surgery is associated with an increased risk of postoperative venous thromboembolism (VTE). This study aimed to compare the predictive accuracy of the Caprini risk score (CRS 2005, 2010, and a population-specific version) for postoperative VTE in obese patients undergoing bariatric surgery.MethodsA prospective observational study was conducted from 2020 to 2025, involving 120 patients aged 26-75 years with obesity (BMI, 35-85 kg/m2) undergoing laparoscopic bariatric surgery. VTE risk factors were assessed, including visceral fat area by computed tomography, estimated fat apron weight (FAW), severe obstructive sleep apnea (sOSA), CO2-pneumoperitoneum pressure, and popliteal vein blood flow measured intraoperatively via Doppler ultrasound scan. The primary outcome combined asymptomatic and symptomatic deep vein thrombosis (DVT) and symptomatic pulmonary embolism (PE) within 30 days postoperatively.ResultsThe incidence of postoperative VTE was 5.0% (95% CI, 2.3-10.5%), including one symptomatic PE (0.8%). Regression analysis identified CRS 2010, the estimated FAW, and sOSA as significant predictors of VTE. In the modified CRS, a FAW ≥11 kg was assigned 1 point, and the presence of sOSA was assigned 3 points. The improved predictive accuracy was observed with the CRS 2010, considering sOSA (AUC, 0.866; 95% CI, 0.794-0.939) and sOSA with FAW (AUC, 0.862; 95% CI, 0.784-0.939). The optimal cut-off value was ≥12 points (sensitivity 83%, specificity 81%).ConclusionsIn bariatric surgery, CRS 2010 with sOSA and FAW showed a potential improvement in predicting postoperative VTE, with scores ≥12 indicating the highest risk. Although these findings remain preliminary and require further validation.

减肥手术中不同修改的capriti风险评分的比较分析。
背景:减肥手术与术后静脉血栓栓塞(VTE)风险增加相关。本研究旨在比较capriti风险评分(CRS 2005、2010和特定人群版本)对接受减肥手术的肥胖患者术后静脉血栓栓塞的预测准确性。方法前瞻性观察研究于2020年至2025年,纳入120例26-75岁肥胖(BMI, 35-85 kg/m2)行腹腔镜减肥手术的患者。评估静脉血栓栓塞的危险因素,包括通过计算机断层扫描测量的脏脂肪面积、估计的脂肪围重(FAW)、严重阻塞性睡眠呼吸暂停(sOSA)、co2 -气腹压力和术中通过多普勒超声扫描测量的腘静脉血流。术后30天内无症状和有症状的深静脉血栓形成(DVT)和有症状的肺栓塞(PE)。结果术后静脉血栓栓塞发生率为5.0% (95% CI, 2.3 ~ 10.5%),其中1例有症状性PE(0.8%)。回归分析发现CRS 2010、估计的FAW和sOSA是VTE的重要预测因子。在改进后的CRS中,FAW≥11 kg评分为1分,存在sOSA评分为3分。考虑到sOSA (AUC, 0.866; 95% CI, 0.794-0.939)和sOSA与FAW (AUC, 0.862; 95% CI, 0.784-0.939), CRS 2010的预测准确性得到了提高。最佳临界值≥12点(灵敏度83%,特异性81%)。结论在减肥手术中,CRS 2010与sOSA和FAW在预测术后静脉血栓栓塞方面有潜在的改善,评分≥12为最高风险。尽管这些发现仍然是初步的,需要进一步的验证。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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