Serial MRI documentation of sequestrated lumbar disc resorption during conservative management: a case report.

IF 2.5 Q2 CLINICAL NEUROLOGY
Frontiers in pain research (Lausanne, Switzerland) Pub Date : 2026-09-03 eCollection Date: 2026-01-01 DOI:10.3389/fpain.2026.1853632
Zhou Zhang, Zhiliang Yang, Yongqi Zhao, Yuchen Guo, Guangwen Wu
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Abstract

Background: Although spontaneous resorption in lumbar disc herniation (LDH) is a recognized phenomenon, systematic visual evidence of its temporal progression remains limited. This report utilizes short-interval serial magnetic resonance imaging (MRI) to document the longitudinal clinico-radiological evolution of a sequestrated LDH managed within an integrative conservative framework, providing a continuous imaging-clinical timeline linking structural resolution to symptomatic recovery.

Case presentation: A 33-year-old man presented with acute-onset low back pain and right lower limb radicular pain. MRI demonstrated a right posterolateral L4/5 disc extrusion with sequestration, featuring peripheral contrast enhancement (the "bull's-eye" sign). After declining non-steroidal anti-inflammatory drugs (NSAIDs), the patient opted for a 16-week integrative regimen comprising acupuncture and modified Duhuo Jisheng decoction. Serial MRI across five time points enabled high-resolution longitudinal tracking of morphological changes. Imaging documented the complete resorption of the free sequestrated fragment, achieving a 79.3% reduction in the herniation ratio alongside a 77.7% reduction in the cross-sectional area at 4 months. These morphological adjustments coincided with substantial clinical recovery, with the Visual Analogue Scale (VAS) score decreasing from 8 to 0 and the Japanese Orthopaedic Association (JOA) score improving from 5 to 28. A 5-month post-treatment follow-up confirmed sustained resolution without recurrence, showing only residual L4/5 disc bulging.

Conclusions: Serial MRI dynamically captured the progressive resorption of a sequestrated L4/5 disc and its concordant clinical recovery during integrative conservative management. While this approach was temporally associated with favorable outcomes, the observational design precludes definitive causal attribution. This report suggests that such management may provide a supportive clinical window allowing spontaneous resorption to proceed; however, higher-level controlled studies are required to differentiate potential therapeutic modulation from the natural history of disc regression.

保守治疗期间隔离腰椎间盘吸收的连续MRI记录:1例报告。
背景:虽然腰椎间盘突出症(LDH)的自发吸收是一种公认的现象,但其时间进展的系统视觉证据仍然有限。本报告利用短间隔连续磁共振成像(MRI)记录了在综合保守框架内管理的隔离LDH的纵向临床放射学演变,提供了将结构解决与症状恢复联系起来的连续成像-临床时间表。病例介绍:一名33岁男性,表现为急性腰痛和右下肢神经根性疼痛。MRI显示右侧后外侧L4/5椎间盘突出伴隔离,周围对比增强(“靶心”征)。在停止使用非甾体抗炎药(NSAIDs)后,患者选择了16周的综合治疗方案,包括针灸和加味的独活生汤。连续MRI跨越五个时间点实现了形态学变化的高分辨率纵向跟踪。影像学记录显示游离隔离碎片完全吸收,4个月时疝发生率降低79.3%,横截面积减少77.7%。这些形态学调整与临床的显著恢复相吻合,视觉模拟量表(VAS)评分从8分下降到0分,日本骨科协会(JOA)评分从5分提高到28分。治疗后5个月随访证实持续消退无复发,仅显示残留的L4/5椎间盘突出。结论:在综合保守治疗期间,序列MRI动态捕获了隔离的L4/5椎间盘的逐渐吸收及其一致的临床恢复。虽然这种方法暂时与有利的结果相关,但观察设计排除了明确的因果归因。该报告表明,这种管理可能提供一个支持性的临床窗口,允许自发吸收进行;然而,需要更高水平的对照研究来区分潜在的治疗调节与椎间盘退化的自然历史。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
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