{"title":"Rapidly progressive calcinosis cutis in adult-onset dermatomyositis: A case report.","authors":"Elona Bebla, Attiya Haroon","doi":"10.1177/2050313X261463982","DOIUrl":null,"url":null,"abstract":"<p><p>Calcinosis cutis is an uncommon but clinically significant complication of dermatomyositis, occurring in approximately 11%-20% of adult patients. We report a case of rapidly progressive, extensive calcinosis cutis in a 52-year-old woman with adult-onset dermatomyositis. Despite ongoing systemic immunosuppressive therapy, she developed biopsy-confirmed calcinosis within 3 months of initial presentation, with subsequent extension to the bilateral axillae, anterior chest wall, and proximal thighs causing functional impairment. Myositis-specific antibody panel results are pending. This case illustrates the aggressive potential of calcinosis in adult dermatomyositis, the limited therapeutic options once calcification is established, and the importance of early aggressive disease control.</p>","PeriodicalId":21418,"journal":{"name":"SAGE Open Medical Case Reports","volume":"14 ","pages":"2050313X261463982"},"PeriodicalIF":0.6000,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13583267/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"SAGE Open Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/2050313X261463982","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Calcinosis cutis is an uncommon but clinically significant complication of dermatomyositis, occurring in approximately 11%-20% of adult patients. We report a case of rapidly progressive, extensive calcinosis cutis in a 52-year-old woman with adult-onset dermatomyositis. Despite ongoing systemic immunosuppressive therapy, she developed biopsy-confirmed calcinosis within 3 months of initial presentation, with subsequent extension to the bilateral axillae, anterior chest wall, and proximal thighs causing functional impairment. Myositis-specific antibody panel results are pending. This case illustrates the aggressive potential of calcinosis in adult dermatomyositis, the limited therapeutic options once calcification is established, and the importance of early aggressive disease control.
期刊介绍：
SAGE Open Medical Case Reports (indexed in PubMed Central) is a peer reviewed, open access journal. It aims to provide a publication home for short case reports and case series, which often do not find a place in traditional primary research journals, but provide key insights into real medical cases that are essential for physicians, and may ultimately help to improve patient outcomes. SAGE Open Medical Case Reports does not limit content due to page budgets or thematic significance. Papers are subject to rigorous peer review and are selected on the basis of whether the research is sound and deserves publication. By virtue of not restricting papers to a narrow discipline, SAGE Open Medical Case Reports facilitates the discovery of the connections between papers, whether within or between disciplines. Case reports can span the full spectrum of medicine across the health sciences in the broadest sense, including: Allergy/Immunology Anaesthesia/Pain Cardiovascular Critical Care/ Emergency Medicine Dentistry Dermatology Diabetes/Endocrinology Epidemiology/Public Health Gastroenterology/Hepatology Geriatrics/Gerontology Haematology Infectious Diseases Mental Health/Psychiatry Nephrology Neurology Nursing Obstetrics/Gynaecology Oncology Ophthalmology Orthopaedics/Rehabilitation/Occupational Therapy Otolaryngology Palliative Medicine Pathology Pharmacoeconomics/health economics Pharmacoepidemiology/Drug safety Psychopharmacology Radiology Respiratory Medicine Rheumatology/ Clinical Immunology Sports Medicine Surgery Toxicology Urology Women''s Health.
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