{"title":"Streptococcal pharyngitis, infectious mononucleosis, or both? A diagnostic dilemma in pediatric pharyngitis.","authors":"Kazuki Iio, Horton James Lee, Evridiki Fera","doi":"10.1093/pch/pxag080","DOIUrl":null,"url":null,"abstract":"<p><p>Infectious mononucleosis (IM) is a common cause of pharyngitis in children, particularly among adolescents. IM is a self-limiting condition, and differentiating it from other causes of pharyngitis that require treatment is key to its management. One such condition is group A streptococcal (GAS) pharyngitis, which can be complicated by acute rheumatic fever if left untreated. In this report, we present a case of suspected IM with a positive GAS rapid antigen detection test, highlight the evidence surrounding these two conditions, and discuss the clinical dilemma of performing GAS testing in patients with an IM-like presentation.</p>","PeriodicalId":19730,"journal":{"name":"Paediatrics & child health","volume":"31 6","pages":"620-623"},"PeriodicalIF":2.5000,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13580635/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Paediatrics & child health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/pch/pxag080","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/9/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
Infectious mononucleosis (IM) is a common cause of pharyngitis in children, particularly among adolescents. IM is a self-limiting condition, and differentiating it from other causes of pharyngitis that require treatment is key to its management. One such condition is group A streptococcal (GAS) pharyngitis, which can be complicated by acute rheumatic fever if left untreated. In this report, we present a case of suspected IM with a positive GAS rapid antigen detection test, highlight the evidence surrounding these two conditions, and discuss the clinical dilemma of performing GAS testing in patients with an IM-like presentation.
期刊介绍:
Paediatrics & Child Health (PCH) is the official journal of the Canadian Paediatric Society, and the only peer-reviewed paediatric journal in Canada. Its mission is to advocate for the health and well-being of all Canadian children and youth and to educate child and youth health professionals across the country.
PCH reaches 8,000 paediatricians, family physicians and other child and youth health professionals, as well as ministers and officials in various levels of government who are involved with child and youth health policy in Canada.