A novel carbon black-integrated cage-structured NiCo2O4 nanocomposite for the selective and sensitive electrochemical determination of vanillin

IF 5.4 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchimica Acta Pub Date : 2026-09-18 DOI:10.1007/s00604-026-08405-9

Li Zhang, Shuiying Xiong, Liting Jiang, Jiaxin Qiu, Qian Jin, Xinding Lv, Xinman Tu

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引用次数: 0

Abstract

A novel electrochemical sensor for determination of vanillin based on carbon black and NiCo₂O₄ nanocomposite (CB@NiCo₂O₄) was established. The nanocomposite was immobilized onto electrode surface, the carbon black can selectively adsorb vanillin via π-π stacking interactions between the aromatic domains and the benzene ring of vanillin. Concurrently, the NiCo₂O₄ with cage-structure enhances the electrochemical signal response of the adsorbed vanillin by the high specific surface area and favorable ion-exchange capability. Under optimized experimental conditions, the sensor exhibits a linear range of 0.1 ~ 60 µM with a limit of detection of 30 nM, and the selectivity and signal stability were confirmed to be satisfactory. In real-sample analysis, the results are agreement with the contrast testing results of high-performance liquid chromatography, and the spike recovery experiment values ranged from 95.35% to 103.80%, with relative standard deviations (RSDs) of 3.77%~4.59% (n = 3). The proposed electrochemical sensor possesses a favorable application prospect in product quality control.

Graphical abstract

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一种新型炭黑集成笼状NiCo2O4纳米复合材料，用于电化学测定香兰素的选择性和敏感性

建立了一种基于炭黑和NiCo2O4纳米复合材料（CB@NiCo2O4）的新型香兰素电化学传感器。将纳米复合材料固定在电极表面，炭黑通过芳香结构域与香兰素苯环之间的π-π堆叠相互作用选择性吸附香兰素。同时，具有笼状结构的NiCo2O4凭借其较高的比表面积和良好的离子交换能力增强了所吸附的香兰素的电化学信号响应。在优化的实验条件下，传感器的线性范围为0.1 ~ 60µM，检测限为30 nM，具有良好的选择性和信号稳定性。实际样品分析结果与高效液相色谱对比试验结果一致，峰回收率实验值范围为95.35% ~ 103.80%，相对标准偏差（rsd）为3.77%~4.59% （n = 3）。所提出的电化学传感器在产品质量控制方面具有良好的应用前景。图形抽象

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来源期刊

Microchimica Acta 化学-分析化学

CiteScore

9.80

自引率

5.30%

发文量

410

审稿时长

2.7 months

期刊介绍： As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.